65452-72-4Relevant academic research and scientific papers
Cu(OH)(TMEDA)2Cl2-catalyzed regioselective 2-arylation of 5-substituted tetrazoles with boronic acids under mild conditions
Onaka, Takuya,Umemoto, Hideaki,Miki, Yasuyoshi,Nakamura, Akira,Maegawa, Tomohiro
, p. 6703 - 6707 (2014)
A mild and regioselective 2-arylation of 5-substituted tetrazoles is described. The reaction proceeds regioselectively with a variety of arylboronic acids in the presence of [Cu(OH)(TMEDA)]2Cl2 to afford 2,5-disubstituted tetrazoles. This is the first report of highly regioselective arylation of 5-alkyltetrazoles.
5-substituted-2-2H-tetrazoleamine manufacturing method
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Paragraph 0030-0032; 0035; 0040, (2021/09/18)
The present invention is a method for producing a 5-substituted-2-aryl-2H-tetrazole that is useful as an intermediate for producing a pharmaceutical compound, and relates to a method which selectively introduces an aryl group in the 2 position.
Heterocyclic derivatives of fullerene C60. 1. Synthesis of new fulleropyrazolines by the 1,3-dipolar cycloaddition of nitrile imines
Reinov,Yurovskaya,Davydov,Streletskii
, p. 188 - 193 (2007/10/03)
New stable [6,6]-closed cycloadducts, fulleropyrazolines containing aryl, hetaryl, trifluoromethyl, and other substituents in the five-membered ring, have been obtained by the 1,3-dipolar cycloaddition of nitrile imines to C 60. Two methods of generating nitrile imines in situ have been used, the dehydrohalogenation of the corresponding hydrazonoyl halides by the action of triethylamine and the thermal decomposition of 2,5-diaryltetrazoles.
Palladium- and copper-catalyzed selective arylation of 5-aryltetrazoles by diaryliodonium salts
Beletskaya, Irina P.,Davydov, Dmitri V.,Gorovoy, Matvey S.
, p. 6221 - 6223 (2007/10/03)
Palladium(0)-catalyzed arylation of 5-aryltetrazoles in t-BuOH at 80°C with diaryliodonium salts proceeds in the presence of copper(II) phenylcyclopropyl carboxylate regioselectively at the N2 position.
