654635-41-3

Basic information

• Product Name: 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline
• Synonyms: 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline
• CAS NO: 654635-41-3
• Molecular Weight: 331.34
• Mol File: 654635-41-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline(654635-41-3)
• EPA Substance Registry System: 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline(654635-41-3)

Safety Data

• Hazardous Substances Data: 654635-41-3(Hazardous Substances Data)

Upstream product

• 1207102-84-8 2-(4-methylphenyl)-9-(trifluoromethyl)-5,6,7,8,8a,9-hexahydropyrazolo[5,1-b]quinazoline-4a,9(4H)-diol 
• 387-89-3 2-(2,2,2-trifluoroacetyl)cyclohexanone 
• 151293-15-1 5-amino-3-(4-methylphenyl)-1H-pyrazole 

Relevant articles and documents

Highly regioselective synthesis of trifluoromethyl derivatives of pyrazolo[1,5-a]pyrimidines bearing fused cycloalkane rings using (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones

8-Trifluoromethyl-6,7-dihydro-5H-1,4,8a-triaza-s-indacene and 9-trifluoromethyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolines were efficiently generated by condensation of 5(3)-aminopyrazoles with (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones and isolated in excellent yields. The regiochemistry of the prepared compounds was established by 1H, 13C and 19F NMR spectroscopy and X-ray diffraction analysis.