654640-19-4Relevant academic research and scientific papers
Construction of chiral quaternary carbon centers by Pd-catalyzed asymmetric allylic substitution with P,N-1,1′-ferrocene ligands
Hou, Xue-Long,Sun, Na
, p. 4399 - 4401 (2004)
(Chemical equation presented) A chiral quaternary carbon center on allyl substrates was constructed by Pd-catalyzed allylic alkylation reaction in good to high regio- and enantioselectivities for a wide range of substrates for the first time.
Gold(I)-catalyzed [2 + 2]-cycloaddition of allenenes
Luzung, Michael R.,Mauleon, Pablo,Toste, F. Dean
, p. 12402 - 12403 (2008/09/17)
A cationic phosphinegold(I)-catalyzed intramolecular [2 + 2]-cycloaddition between an allene and an alkene to form alkylidene?cyclobutanes is described. Additionally, the reported cycloisomerization reaction provides access to enantioenriched bicyclo-[3.2.0] structures using chiral biarylphosphinegold(I) complexes as catalysts. Copyright
Palladium-Catalyzed Highly Regio- and Stereoselective Addition of Organoboronic Acids to Allenes in the Presence of AcOH
Ma, Shengming,Jiao, Ning,Ye, Longwu
, p. 6049 - 6056 (2007/10/03)
The Pd0-catalyzed regio- and stereoselective addition of organoboronic acids to allenes leads to stereodefined tri- or tetrasubstituted alkenes. Furthermore, this method shows high substitutent-loading capability and tolerance of various substitutents. A hydropalladation-Suzuki coupling mechanism, which may account for the regio- and stereoselectivity, is proposed.
