654644-03-8

Upstream product

• 187040-03-5 4-methylbenzo[1,3]dioxol-5-ol 
• 533-31-3 Sesamol 
• 111726-43-3 3,4-(methylenedioxy)phenyl methoxymethyl ether 
• 854021-83-3 (5R,7S,10R)-11-Allyloxy-2,2,12-trimethyl-4,5,7,10-tetrahydro-1,3,15,17-tetraoxa-6-aza-cyclopenta[a]phenanthrene-6,7-dicarboxylic acid 7-ethyl ester 6-(2,2,2-trichloro-ethyl) ester 
• 654644-00-5 (4S,5aR,9aR)-ethyl 10-(allyloxy)-8,8,11-trimethyl-5,5a,6,9a-tetrahydro-4H-[1,3]dioxino[5,4-c][1,3]dioxolo[4,5-h]isoquinoline-4-carboxylate 
• 654644-02-7 (4R,5aR,9aR)-ethyl 10-(allyloxy)-8,8,11-trimethyl-5,5a,6,9a-tetrahydro-4H-[1,3]dioxino[5,4-c][1,3]dioxolo[4,5-h]isoquinoline-4-carboxylate 
• 654643-99-9 [(4R,5R)-4-(6-Allyloxy-7-methyl-benzo[1,3]dioxol-5-yl)-2,2-dimethyl-[1,3]dioxan-5-yl]-carbamic acid tert-butyl ester 
• 654643-98-8 (R)-4-[(R)-Hydroxy-(6-hydroxy-7-methyl-benzo[1,3]dioxol-5-yl)-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 654643-97-7 (4R,5R)-4-(6-Allyloxy-7-methyl-benzo[1,3]dioxol-5-yl)-2,2-dimethyl-[1,3]dioxan-5-ylamine 
• 426213-78-7 [(1R,2R)-2-(6-Allyloxy-7-methyl-benzo[1,3]dioxol-5-yl)-2-hydroxy-1-hydroxymethyl-ethyl]-carbamic acid tert-butyl ester 
• 187040-02-4 5-methoxy methoxy-4-methyl benzo[d][1,3]dioxole 
• 96845-11-3 (R)-N-2,2,2-trichloroethoxycarbonyl-(S-trityl)cysteine 
• 654643-96-6 (11-allyloxy-2,2,12-trimethyl-5,6,7,10-tetrahydro-4H-1,3,15,17-tetraoxa-6-aza-cyclopenta[a]phenanthren-7-yl)-methanol 

Downstream Products

• 654644-04-9 C₄₁H₃₉Cl₃N₂O₈S 

Relevant academic research and scientific papers

Synthetic studies toward ecteinascidin 743

An efficient synthesis of a fully functionalized tetracycle (A-B-C-H) 7 containing a 1,4-bridged 10-membered lactone was developed. Phenolic aldol condensation between 2-methylsesamol (15) and Garner's aldehyde provided the protected amino diol 16, which

Synthetic studies on ecteinascidin 743: Rapid access to the fully functionalized tetrahydroisoquinoline with a bridged 10-membered sulfur containing macrocycle

Synthesis of tetrahydroisoquinoline with a 1,4-bridged 10-membered sulfur containing macrolactone (5) is described. Phenolic aldolisation, Pictet-Spengler cyclisation of an acid sensitive amino diol under newly developed conditions (LiBr, toluene-TFE, 80°