654666-62-3 Usage
General Description
The chemical compound 1(2H)-Pyridinecarboxylic acid, 4-(aminocarbonyl)-3,6-dihydro-, methyl ester, also known as Niacinamide, is a derivative of niacin, or vitamin B3. It is commonly used in skincare products for its anti-inflammatory and antioxidant properties, making it effective in treating conditions such as acne, eczema, and hyperpigmentation. Niacinamide is also known to improve the skin's barrier function, reduce the appearance of fine lines and wrinkles, and regulate oil production. Additionally, it is used in the synthesis of pharmaceuticals and as a nutritional supplement for its role in maintaining overall skin health and function.
Check Digit Verification of cas no
The CAS Registry Mumber 654666-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,4,6,6 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 654666-62:
(8*6)+(7*5)+(6*4)+(5*6)+(4*6)+(3*6)+(2*6)+(1*2)=193
193 % 10 = 3
So 654666-62-3 is a valid CAS Registry Number.
654666-62-3Relevant articles and documents
Aza-THIP and related analogues of THIP as GABAC antagonists
Krehan, Dorte,Frolund, Bente,Ebert, Bjarke,Nielsen, Birgitte,Krogsgaard-Larsen, Povl,Johnston, Graham A. R.,Chebib, Mary
, p. 4891 - 4896 (2003)
The potency of a series of eight compounds structurally related with 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP), a potent GABA A partial agonist exhibiting GABAC ρ1 antagonist effect (Ki=25 μM), was d