65488-98-4Relevant academic research and scientific papers
NOVEL BETA-CARBOLINES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHSR) ANTAGONISTS
-
Page/Page column 112-113, (2008/06/13)
The present invention relates to compounds of Formula (I): Formula (I) wherein R-R, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.
Piperazine alkanols
-
, (2008/06/13)
This invention relates to variously substituted piperazine derivatives. S compounds possess therapeutically useful vasodilator properties.
