6549-57-1 Usage
Uses
Used in Fragrance Industry:
8-Methyl-1-naphthalenecarboxaldehyde is used as a fragrance ingredient for its ability to impart a strong, floral scent to consumer products such as perfumes, soaps, and cosmetics. Due to its potent aroma, it is typically used in small quantities to enhance the overall scent profile of these products.
Used in Flavoring Industry:
In the food industry, 8-Methyl-1-naphthalenecarboxaldehyde is utilized as a flavoring agent to add unique taste and aroma characteristics to various food products.
Used in Chemical Synthesis:
8-Methyl-1-naphthalenecarboxaldehyde also serves as a building block in the synthesis of other chemicals, contributing to the creation of a range of different chemical products.
Safety Note:
It is important to handle 8-Methyl-1-naphthalenecarboxaldehyde with care, as it may cause irritation to the skin, eyes, and respiratory system if not used properly, highlighting the need for appropriate safety measures during its application.
Check Digit Verification of cas no
The CAS Registry Mumber 6549-57-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,4 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6549-57:
(6*6)+(5*5)+(4*4)+(3*9)+(2*5)+(1*7)=121
121 % 10 = 1
So 6549-57-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H14Cl2N2O4/c1-25-13-6-4-3-5-11(13)21-16-15(20)17(23)22(18(16)24)12-9-10(19)7-8-14(12)26-2/h3-9,21H,1-2H3
6549-57-1Relevant academic research and scientific papers
Ortho Metalation Directed by α-Amino Alkoxides
Comins, Daniel L.,Brown, Jack D.
, p. 1078 - 1083 (2007/10/02)
The addition of aromatic aldehydes to certain lithium dialkylamides in benzene or tetrahydrofuran gave α-amino alkoxides which were ortho lithiated with excess n-butyllithium.Subsequent alkylation and hydrolysis provided ortho-substituted aromatic aldehydes via a one-pot reaction.The ortho metalation of α-amino alkoxides derived from 1- and 2-naphthaldehyde and various substituted benzaldehydes was examined.When N,N,N'-trimethylethylenediamine was used as the amine component of the α-amino alkoxide, metalation could be carried out at lower temperatures.This rate increase is due to an intramolecular TMEDA-like assisted metalation.The synthetic utility of this ortho metalation, including how varying the amine component of the α-amino alkoxide affects the regiochemistry and metalation rate, is discussed.
