65492-59-3

Usage

Uses

Used in Pharmaceutical Industry:
2-[hydroxy(4-methoxyphenyl)methyl]-N-phenylbenzamide is used as a potential drug candidate for various therapeutic applications due to its unique structure and functional groups. The hydroxy and methoxy groups on the benzene ring may allow for interactions with biological targets, while the benzamide moiety suggests potential as an inhibitor or modulator of enzymatic activity. Further research and testing may be necessary to fully understand the properties and potential uses of 2-[hydroxy(4-methoxyphenyl)methyl]-N-phenylbenzamide in drug design and development.

Upstream product

• 93-98-1 N-phenyl benzoyl amide 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 21615-74-7 3-(4-methoxyphenyl)phthalide 

Relevant academic research and scientific papers

Conversion of 3-arylphthalides into anthrones with a methylcarbonyl substituent at the C-10 position

The ortho-lithiation of a benzoic acid anilide followed by condensation with an aryl aldehyde gave a 3-arylphthalide. Reductive alkylation with 1-methoxy-1-trimethylsilyloxyethene gave a substituted aromatic carboxylic acid which was cyclised to an anthro

Application of organolithium and related reagents in synthesis. XXVII.[1] Effect of the nucleophilic character of silyl enol ethers upon the conversion of 3-arylphthalides into 2-(1-Aryl-2-methoxycarbonyl) benzoic acids

A convenient two step protocol preparation of the ortho-alkylated (by secondary substituent with the carbomethoxy group at the end of alkyl chain) aromatic carboxylic acids 6 from benzoic acids anilides 1 was developed, which exploited the reductive alkylation of phthalides 4 with silyl vinyl ethers 5a-b or silyl ketene acetals 5c-g as a key step, is described.