65517-27-3 Usage
Description
Metaclazepam is a benzodiazepine anxiolytic with an antidepressant component. In man,
it is reported to produce only minimal sedative and muscle relaxant side-effects.
Originator
Kali-Chemie (W. Germany)
Uses
Antiseptic (topical); antifungal; antifungal (veterinary).
Brand name
Talis
Check Digit Verification of cas no
The CAS Registry Mumber 65517-27-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,1 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65517-27:
(7*6)+(6*5)+(5*5)+(4*1)+(3*7)+(2*2)+(1*7)=133
133 % 10 = 3
So 65517-27-3 is a valid CAS Registry Number.
InChI:InChI=1S/C18H18BrClN2O/c1-22-13(11-23-2)10-21-18(14-5-3-4-6-16(14)20)15-9-12(19)7-8-17(15)22/h3-9,13H,10-11H2,1-2H3
65517-27-3Relevant articles and documents
1,4-Benzodiazepine and 1,5-benzodiazocines. VII. Synthesis and biological activity
Milkowski,Liepman,Zeugner,et al.
, p. 345 - 358 (2007/10/02)
Synthesis of a new class of 2,3,-dihydro-1H-1,4-benzodiazepines and of the corresponding 1,2,3,4-tetrahydro-1,5-benzodiazocines is described. The biological activity of the compounds is evaluated in vivo by measuring their inhibition of pentetrazole induced seizures and in vitro by determining their affinity for the benzodiazepine receptor. Comparison of both tests reveals differences between activity in vivo and in vitro which are discussed.
