655231-89-3Relevant academic research and scientific papers
7-Methyl trimethoprim analogues as inhibitors of the folate metabolizing enzymes
Gangjee, Aleem,Lin, Xin,Queener, Sherry F.
, p. 507 - 512 (2007/10/03)
A series of 5-(1-phenylethyl)pyrimidines 2-10 (Table I) were designed and synthesized as potent and selective inhibitors of Pneumocystis carinii (P. carinii), Toxoplasma gondii (T. gondii) and Mycobacterium avium (M. avium) dihydrofolate reductases (DHFR)
