655237-27-7Relevant academic research and scientific papers
Synthesis and biological evaluation of C-glucosides with azulene rings as selective SGLT2 inhibitors for the treatment of type 2 diabetes mellitus: Discovery of YM543
Ikegai, Kazuhiro,Imamura, Masakazu,Suzuki, Takayuki,Nakanishi, Keita,Murakami, Takeshi,Kurosaki, Eiji,Noda, Atsushi,Kobayashi, Yoshinori,Yokota, Masayuki,Koide, Tomokazu,Kosakai, Kazuhiro,Ohkura, Yasufumi,Takeuchi, Makoto,Tomiyama, Hiroshi,Ohta, Mitsuaki
, p. 3934 - 3948 (2013/07/19)
Here, a series of C-glucosides with azulene rings in the aglycon moiety was synthesized and the inhibitory activities toward hSGLT1 and hSGLT2 were evaluated. Starting from the azulene derivative 7 which had relatively good SGLT2 inhibitory activity, comp
Azulene derivatives and salts thereof
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Page/Page column 9, (2010/02/11)
The present invention provides an azulene derivative and a salt thereof, wherein an azulene ring is bonded to a benzene ring directly or via a lower alkylene which may be substituted with a halogen atom and the benzene ring is directly bonded to the gluco
