655243-99-5

Upstream product

• 591742-16-4 3-chloro-5,6-dihydroxy-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 478400-02-1 methyl 7-chloro-1,3-dioxa-5-thia-s-indacene-6-carboxylate 
• 137278-46-7 3-chloro-5,6-methylenedioxybenzothiophene-2-carbonyl chloride 

Downstream Products

• 655247-87-3 5,6-bis-(4-benzenesulfonyl-benzyloxy)-3-(4-chloro-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655246-27-8 5,6-bis-(4-benzenesulfonyl-benzyloxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655244-14-7 [5,6-bis-(4-benzenesulfonyl-benzyloxy)-3-chloro-benzo[b]thiophen-2-yl]-methanol 

Relevant academic research and scientific papers

New fibrinolytic agents: Benzothiophene derivatives as inhibitors of the t-PA-PAI-1 complex formation

The synthesis and activity of novel benzothiophene derivatives are described. In the t-Pa-induced fibrin clot lysis assay, several compounds inhibit the formation of the tPa-PAI-1 complex with submicromolar IC50. This class of compounds potentially represents a new generation of antithrombotic-fibrinolytic agents.