137278-46-7

Upstream product

• 2373-80-0 3,4-(methylenedioxy)cinnamic acid 
• 2373-80-0 3,4-methylenedioxy-trans-cinnamic acid 

Downstream Products

• 137278-49-0 3-chloro-5,6-methylenedioxy-N-phenylbenzothiophene-2-carboxamide 
• 655246-02-9 5,6-bis-(biphenyl-2-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655246-04-1 5,6-bis-(biphenyl-4-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655246-03-0 5,6-bis-(biphenyl-3-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655244-06-7 [5,6-bis-(biphenyl-3-ylmethoxy)-3-chloro-benzo[b]thiophen-2-yl]-methanol 
• 655244-08-9 [5,6-bis-(biphenyl-4-ylmethoxy)-3-chloro-benzo[b]thiophen-2-yl]-methanol 
• 655244-05-6 [5,6-bis-(biphenyl-2-ylmethoxy)-3-chloro-benzo[b]thiophen-2-yl]-methanol 
• 655246-26-7 3-chloro-5,6-bis-(4-phenylsulfanyl-benzyloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655246-25-6 3-chloro-5,6-bis-(4-phenoxy-benzyloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655233-62-8 5,6-bis-(biphenyl-3-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 655246-10-9 5,6-bis-(4-benzyl-benzyloxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655233-27-5 5,6-bis-(biphenyl-2-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 655233-82-2 5,6-bis-(biphenyl-4-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 655244-12-5 [3-chloro-5,6-bis-(4-phenoxy-benzyloxy)-benzo[b]thiophen-2-yl]-methanol 

Relevant academic research and scientific papers

Dioxolobenzothienoquinolin-6(5H)-ones

The reaction of 3,4-methylenedioxycinnamic acid (1) with thionyl chloride resulted in the formation of 7-chlorothieno-1,3-benzodioxole-6-carbonyl chloride (2) and cinnamoyl chloride (3).Subsequent reaction of the former with p-substituted anilines

New fibrinolytic agents: Benzothiophene derivatives as inhibitors of the t-PA-PAI-1 complex formation

The synthesis and activity of novel benzothiophene derivatives are described. In the t-Pa-induced fibrin clot lysis assay, several compounds inhibit the formation of the tPa-PAI-1 complex with submicromolar IC50. This class of compounds potentially represents a new generation of antithrombotic-fibrinolytic agents.

Benzothiophene, benzofuran and indole compounds

A compound selected from those of formula (I): wherein: X represents oxygen, sulphur, or NR3wherein R3is as defined in the description, Y represents oxygen, sulphur, NR3, or may represent single bond in certain cases, T re