655244-08-9

Upstream product

• 591742-16-4 3-chloro-5,6-dihydroxy-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 478400-02-1 methyl 7-chloro-1,3-dioxa-5-thia-s-indacene-6-carboxylate 
• 137278-46-7 3-chloro-5,6-methylenedioxybenzothiophene-2-carbonyl chloride 
• 655233-82-2 5,6-bis-(biphenyl-4-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carboxylic acid methyl ester 

Downstream Products

• 655246-04-1 5,6-bis-(biphenyl-4-ylmethoxy)-3-chloro-benzo[b]thiophene-2-carbaldehyde 
• 655247-91-9 5,6-bis-(biphenyl-4-ylmethoxy)-3-phenoxy-benzo[b]thiophene-2-carbaldehyde 
• 655247-98-6 5,6-bis-(biphenyl-4-ylmethoxy)-3-(pyridin-3-yloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655247-96-4 5,6-bis-(biphenyl-4-ylmethoxy)-3-(3-fluoro-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655248-09-2 5,6-bis-(biphenyl-4-ylmethoxy)-3-(6-methyl-pyridin-3-yloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655247-72-6 5,6-bis-(biphenyl-4-ylmethoxy)-3-(4-chloro-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655248-24-1 5,6-bis-(biphenyl-4-ylmethoxy)-3-(6-chloro-pyridin-3-yloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655248-82-1 5,6-bis-(biphenyl-4-ylmethoxy)-3-(4-imidazol-1-yl-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655247-94-2 5,6-bis-(biphenyl-4-ylmethoxy)-3-(4-chloro-3-methyl-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655247-92-0 5,6-bis-(biphenyl-4-ylmethoxy)-3-(4-chloro-3-fluoro-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655248-81-0 5,6-bis-(biphenyl-4-ylmethoxy)-3-(quinolin-6-yloxy)-benzo[b]thiophene-2-carbaldehyde 
• 655247-95-3 5,6-bis-(biphenyl-4-ylmethoxy)-3-(4-chloro-3,5-dimethyl-phenoxy)-benzo[b]thiophene-2-carbaldehyde 
• 655248-86-5 5,6-bis-(biphenyl-4-ylmethoxy)-3-[4-(pyridin-4-yloxy)-phenoxy]-benzo[b]thiophene-2-carbaldehyde 

Relevant academic research and scientific papers

New fibrinolytic agents: Benzothiophene derivatives as inhibitors of the t-PA-PAI-1 complex formation

The synthesis and activity of novel benzothiophene derivatives are described. In the t-Pa-induced fibrin clot lysis assay, several compounds inhibit the formation of the tPa-PAI-1 complex with submicromolar IC50. This class of compounds potentially represents a new generation of antithrombotic-fibrinolytic agents.