655245-26-4

Basic information

• Product Name: 2,5,7,12-Tetraoxapentadec-9-en-15-oic acid, 13-methyl-11-oxo-8-[(1S)-1-[(1-oxo-2-propenyl)oxy]ethyl]-, (1S,2R)-2-[(4-methoxyphenyl)methoxy]-1-methyl-3-butenyl ester, (8R,9E,13R)-
• CAS NO: 655245-26-4
• Molecular Formula: C30H42O11
• Molecular Weight: 578.657
• Mol File: 655245-26-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5,7,12-Tetraoxapentadec-9-en-15-oic acid, 13-methyl-11-oxo-8-[(1S)-1-[(1-oxo-2-propenyl)oxy]ethyl]-, (1S,2R)-2-[(4-methoxyphenyl)methoxy]-1-methyl-3-butenyl ester, (8R,9E,13R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5,7,12-Tetraoxapentadec-9-en-15-oic acid, 13-methyl-11-oxo-8-[(1S)-1-[(1-oxo-2-propenyl)oxy]ethyl]-, (1S,2R)-2-[(4-methoxyphenyl)methoxy]-1-methyl-3-butenyl ester, (8R,9E,13R)-(655245-26-4)
• EPA Substance Registry System: 2,5,7,12-Tetraoxapentadec-9-en-15-oic acid, 13-methyl-11-oxo-8-[(1S)-1-[(1-oxo-2-propenyl)oxy]ethyl]-, (1S,2R)-2-[(4-methoxyphenyl)methoxy]-1-methyl-3-butenyl ester, (8R,9E,13R)-(655245-26-4)

Safety Data

• Hazardous Substances Data: 655245-26-4(Hazardous Substances Data)

Upstream product

• 655245-29-7 (-)-1-[3-(4-methoxybenzyloxy)-1-penten-4-yloxycarbonyl]prop-2-yl 5-(tert-butyldimethylsilyloxy)-4-[(2-methoxyethoxy)methoxy]-2-hexenoate 
• 655245-27-5 (3R,4S)-3-(4-methoxybenzyloxy)-1-penten-4-yl (3R)-3-(tert-butyldimethylsilyloxy)butanoate 
• 655245-28-6 (3R,4S)-3-(4-methoxybenzyloxy)-1-penten-4-yl (3R)-3-hydroxybutanoate 
• 566203-43-8 5-(tert-butyl-dimethyl-silanyloxy)-4-(2-methoxy-ethoxymethoxy)-hex-2-enoic acid ethyl ester 
• 196926-52-0 (4R,5S)-(E)-5-(t-butyl(dimethyl)silyloxy)-4-(β-methoxyethoxy)methoxy-2-hexenoic acid 
• 566203-51-8 (3R,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(2-methoxy-ethoxymethoxy)-pentane-1,2-diol 
• 566203-44-9 (3R,4S)-4-(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-1-pentene 
• 566203-41-6 (1S,2R)-tert-butyl-[2-(2-methoxy-ethoxymethoxy)-1-methyl-but-3-enyloxy]-dimethylsilane 
• 566203-42-7 (2S,3S)-3-(tert-butyldimethylsilyloxy)-2-[(2-methoxyethoxy)methoxy]butanal 
• 566203-45-0 (3R,4S)-4-hydroxy-3-(4-methoxybenzyloxy)-1-pentene 
• 132055-83-5 (3R,4S)-4-(tert-butyldimethylsilanyloxy)-pent-1-en-3-ol 
• 212051-17-7 4-methoxybenzyl 2,2,2-trifluoroacetimidate 
• 814-68-6 acryloyl chloride 
• 655245-30-0 (-)-1-[3-(4-methoxybenzyloxy)-1-penten-4-yloxycarbonyl]prop-2-yl 5-hydroxy-4-[(2-methoxyethoxy)methoxy]-2-hexenoate 

Relevant articles and documents

Total Synthesis of Macrosphelides A, B, and E: First Application of Ring-Closing Metathesis for Macrosphelide Synthesis

A new synthetic route for macrosphelides A, B, and E based on ring-closing metathesis (RCM) was established. The substrates for RCM could be synthesized starting from commercially available chiral materials, methyl (S)-lactate and methyl (S)- or (R)-3-hydroxybutyrate, in good overall yields. In the investigation of the key RCM step, it was found that the steric factor around the reaction site significantly affected the reaction rate of macrocyclization. A detailed account regarding this synthetic study is described herein.