655253-59-1 Usage
Imidazole derivative
1-Methyl-4-phenyl-1H-imidazole-5-carbonyl chloride is a carbonyl chloride derivative of imidazole This means that the compound is derived from imidazole by replacing one of its hydrogen atoms with a carbonyl chloride group (C=O) and adding a methyl and phenyl group.
Reactive and unstable intermediate
1-METHYL-4-PHENYL-1H-IMIDAZOLE-5-CARBONYL CHLORIDE is a reactive and unstable intermediate This indicates that the compound is highly reactive and prone to undergo chemical reactions, making it an unstable compound to handle.
Potential to react violently with water and air
The compound must be handled with care due to its potential to react violently with water and air This means that the compound can undergo exothermic reactions when exposed to moisture or air, which can lead to hazardous situations.
Building block in pharmaceutical synthesis
It is commonly used as a building block in the preparation of pharmaceutical drugs and research chemicals This highlights the compound's importance in the synthesis of various pharmaceutical compounds, as it can be used to create more complex molecules with desired properties.
Useful in organic synthesis
Its reactivity makes it useful in organic synthesis The compound's high reactivity allows it to participate in various chemical reactions, making it a valuable tool in the creation of new organic compounds.
Careful handling and storage required
Its use must be carefully controlled to ensure safe handling and storage Due to the compound's reactivity and instability, special precautions must be taken to prevent accidents and ensure the safety of those working with it.
Check Digit Verification of cas no
The CAS Registry Mumber 655253-59-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,5,2,5 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 655253-59:
(8*6)+(7*5)+(6*5)+(5*2)+(4*5)+(3*3)+(2*5)+(1*9)=171
171 % 10 = 1
So 655253-59-1 is a valid CAS Registry Number.
655253-59-1Relevant academic research and scientific papers
Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo
Luke, Richard W.A.,Ballard, Peter,Buttar, David,Campbell, Leonie,Curwen, Jon,Emery, Steve C.,Griffen, Alison M.,Hassall, Lorraine,Hayter, Barry R.,Jones, Cliff D.,McCoull, William,Mellor, Martine,Swain, Mike L.,Tucker, Julie A.
scheme or table, p. 6670 - 6674 (2010/06/12)
The SAR and improvement in potency against Tie2 of novel thienopyrimidine and thiazolopyrimidine kinase inhibitors are reported. The crystal structure of one of these compounds bound to the Tie-2 kinase domain is consistent with the SAR. These compounds h
