65539-69-7

Basic information

• Product Name: 1,3-dihydronaphtho[2,3-c]furan-1-ol
• CAS NO: 65539-69-7
• Molecular Formula: C₁₂H₁₀O₂
• Molecular Weight: 186.2066
• Mol File: 65539-69-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 395.9°C at 760 mmHg
• Flash Point: 202.2°C
• Density: 1.323g/cm³
• Vapor Pressure: 5.59E-07mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 1,3-dihydronaphtho[2,3-c]furan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydronaphtho[2,3-c]furan-1-ol(65539-69-7)
• EPA Substance Registry System: 1,3-dihydronaphtho[2,3-c]furan-1-ol(65539-69-7)

Safety Data

• Hazardous Substances Data: 65539-69-7(Hazardous Substances Data)

Usage

Structure

Naphtho-fused furan with a hydroxyl group

Derivative

Naphtho-fused furan derivative

Functional groups

Furan ring, hydroxyl group

Applications

a. Organic synthesis
b. Building block for pharmaceuticals, agrochemicals, and biologically active molecules
c. Production of fragrances and flavoring agents

Biological activities

a. Antitumor properties
b. Anti-inflammatory properties

Industrial and research applications

Due to its unique structure and potential biological effects

Upstream product

• 939-15-1 2-bromo-3-methylnaphthalene 
• 38399-20-1 2-bromo-3-(bromomethyl)naphthalene 
• 38399-19-8 2-bromo-3-(hydroxymethyl)naphthalene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 15098-01-8 1,4-naphthacenequinone 

Relevant articles and documents

The Preparation and Reactions of Naphthofuran and Naphthofuran

The syntheses of 1,3-dihydro-1- and 1,3-dihydro-3-hydroxynaphthofuran are described.Upon treatment with acid, these compounds undergo 1,4-elimination of water to generate the reactive naphthofuran, which is trapped in situ by a variety of dienophiles.Aromatization of the resulting adducts gives access to 2,3-disubstituted phenanthrenes or benzanthracenes.In addition, it has been shown that the hemiacetal, 1,3-dihydro-1-hydroxynaphthofuran, which exists in tautomeric equilibrium with 3-(hydroxymethyl)-2-naphthaldehyde, serves as a convenient source of naphthofuran.This furan can also be trapped by a variety of dienophiles.The resulting Diels-Alder adducts can be aromatized, giving substituted anthracenes.The use of aromatic 1,4-quinones as dienophiles leads to linear polycyclic aromatic quinones of four to seven rings.