65542-26-9

Basic information

• Product Name: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE
• Synonyms: N-Methyl-4-tert-butylbenzylaMine
• CAS NO: 65542-26-9
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 178.2934
• Mol File: 65542-26-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 239.1°Cat760mmHg
• Flash Point: 89.6°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.0408mmHg at 25°C
• CAS DataBase Reference: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(65542-26-9)
• EPA Substance Registry System: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(65542-26-9)

Safety Data

• Hazardous Substances Data: 65542-26-9(Hazardous Substances Data)

Usage

General Description

N-(4-tert-butylbenzyl)-N-methylamine is a chemical compound with the formula C13H19N. It is a tertiary amine, consisting of a benzyl group attached to a nitrogen atom, with a tert-butyl group attached to the benzyl group. N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE is used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in chemical research and industrial processes. N-(4-tert-butylbenzyl)-N-methylamine is typically handled and stored under controlled conditions due to its reactivity and potential hazards.

InChI:InChI=1/C12H19N/c1-12(2,3)11-7-5-10(6-8-11)9-13-4/h5-8,13H,9H2,1-4H3/p+1

Upstream product

• 67-56-1 methanol 
• 60028-84-4 N-methyl-4-tert-butylbenzoic acid amide 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 

Downstream Products

• 216754-91-5 3'-[N-(4-tert-butylbenzyl)-N-methylaminomethyl]acetophenone 
• 216755-11-2 N-(4-tert-butylbenzyl)-N-methyl-(3-bromo-5-fluorobenzyl)amine 
• 60028-84-4 N-methyl-4-tert-butylbenzoic acid amide 
• 1174338-41-0 5-{[(4-tert-butylbenzyl) (methyl)amino]methyl}-3-phenyl-1,3-oxazolidin-2-one 
• 101846-46-2 N-4-tert-butylbenzyl-N-methyl-3-benzo[b]thiophenemethylamine 
• 216755-16-7 N-(4-tert-butylbenzyl)-N-methyl-(2-bromobenzyl)amine 
• 117427-81-3 2-[2-[[[4-(1,1-dimethylethyl)phenyl]methyl]methylamino]ethyl]-2,3-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(4H)-thione 

Relevant articles and documents

Selective synthesis of mono- and di-methylated amines using methanol and sodium azide as C1 and N1 sources

A Ru(ii) complex mediated synthesis of various N,N-dimethyl and N-monomethyl amines from organic azides using methanol as a methylating agent is reported. This methodology was successfully applied for a one-pot reaction of bromide derivatives and sodium azide in methanol. Notably, by controlling the reaction time several N-monomethylated and N,N-dimethylated amines were synthesized selectively. The practical applicability of this tandem process was revealed by preparative scale reactions with different organic azides and synthesis of an anti-vertigo drug betahistine. Several kinetic experiments and DFT studies were carried out to understand the mechanism of this transformation.

Amine derivatives

The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.