65542-26-9

Basic information

• Product Name: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE
• Synonyms: N-Methyl-4-tert-butylbenzylaMine
• CAS NO: 65542-26-9
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 178.2934
• Mol File: 65542-26-9.mol

Chemical Properties

• Boiling Point: 239.1°Cat760mmHg
• Flash Point: 89.6°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.0408mmHg at 25°C
• CAS DataBase Reference: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(65542-26-9)
• EPA Substance Registry System: N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE(65542-26-9)

Safety Data

• Hazardous Substances Data: 65542-26-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE serves as a chemical intermediate, playing a crucial role in the production of pesticides and other agrochemicals. Its involvement in these processes helps to enhance crop protection and yield.
Used in Organic Compounds Synthesis:
N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE is utilized as a reagent in the synthesis of a wide range of organic compounds. Its versatility in chemical reactions makes it valuable for creating diverse organic molecules for various applications.
Used in Chemical Research:
As a reagent in chemical research, N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE aids scientists in understanding and advancing the field of organic chemistry. Its reactivity and structural features make it an important tool for exploring new chemical reactions and mechanisms.
Used in Industrial Processes:
In industrial applications, N-(4-TERT-BUTYLBENZYL)-N-METHYLAMINE is employed in various chemical processes. Its role in these processes is essential for the production of a multitude of chemical products used across different industries.

InChI:InChI=1/C12H19N/c1-12(2,3)11-7-5-10(6-8-11)9-13-4/h5-8,13H,9H2,1-4H3/p+1

Upstream product

• 67-56-1 methanol 
• 60028-84-4 N-methyl-4-tert-butylbenzoic acid amide 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 

Downstream Products

• 117427-81-3 2-[2-[[[4-(1,1-dimethylethyl)phenyl]methyl]methylamino]ethyl]-2,3-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(4H)-thione 
• 216755-16-7 N-(4-tert-butylbenzyl)-N-methyl-(2-bromobenzyl)amine 
• 216754-91-5 3'-[N-(4-tert-butylbenzyl)-N-methylaminomethyl]acetophenone 
• 101846-46-2 N-4-tert-butylbenzyl-N-methyl-3-benzo[b]thiophenemethylamine 
• 1174338-41-0 5-{[(4-tert-butylbenzyl) (methyl)amino]methyl}-3-phenyl-1,3-oxazolidin-2-one 
• 60028-84-4 N-methyl-4-tert-butylbenzoic acid amide 
• 1431950-41-2 C₂₃H₃₂N₂O₂S 
• 1431950-39-8 C₂₃H₃₄N₂O₂S 
• 216755-11-2 N-(4-tert-butylbenzyl)-N-methyl-(3-bromo-5-fluorobenzyl)amine 

Relevant articles and documents

Selective synthesis of mono- and di-methylated amines using methanol and sodium azide as C1 and N1 sources

A Ru(ii) complex mediated synthesis of various N,N-dimethyl and N-monomethyl amines from organic azides using methanol as a methylating agent is reported. This methodology was successfully applied for a one-pot reaction of bromide derivatives and sodium azide in methanol. Notably, by controlling the reaction time several N-monomethylated and N,N-dimethylated amines were synthesized selectively. The practical applicability of this tandem process was revealed by preparative scale reactions with different organic azides and synthesis of an anti-vertigo drug betahistine. Several kinetic experiments and DFT studies were carried out to understand the mechanism of this transformation.

AZETIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF METABOLIC AND INFLAMMATORY DISEASES

Compounds are disclosed that have a formula represented by the following: These compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example inflammatory conditions, infectious diseases, autoimmune diseases, diseases involving impairment of immune cell functions, cardiometabolic diseases, and/or proliferative diseases.

Amine derivatives

The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.

Antifungal amine derivatives and processing for producing the same

Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1represents a C1-5alkyl group which may be halogenated, R2represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3represents oxygen atom or a methylene group which may be substituted by a C1-4alkyl group; and R4represents 1-or 2 naphthyl group or a phenyl group which may be substituted.