6555-33-5Relevant academic research and scientific papers
Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity
Carceller,Salas,Merlos,Giral,Ferrando,Escamilla,Ramis,García-Rafanell,Forn
, p. 3001 - 3013 (2007/10/03)
This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found it p
Piperidine derivatives with PAF antagonist activity
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, (2008/06/13)
Compounds of general formula I and their salts and solvates are PAF antagonists and as such are useful in the treatment of various diseases or disorders mediated by PAF. Pharmaceutical compositions including these compounds and processes for their prepara
Mesogenic properties of liquid crystals having a chiral semiflexible joint
Gorecha,Pyzuk,Mieczkowski
, p. 33 - 42 (2007/10/02)
Two homologous series of mesogenic enantiomers with chiral semiflexible joint, -C*H(CH3)CH2COO-, are examined. High twist power and presence of blue phases with short lattice period are found for eleven examined compounds. Some effects of chirality in reentrant system are discussed. On phase diagram of enantiomers the SmAd phase area is shifted toward longer homologues as compared to racemates. In result, an island of the SmAd phase in the cholesteric sea exists on binary phase diagrams of R- and S- enantiomers. Triple divergence of the pitch in the cholesteric phase of a pure compound is observed.
