65562-18-7

Upstream product

• 34705-89-0 5-benzylidenerhodanine sodium 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 3806-42-6 5-benzylidene-2-thioxothiazolidin-4-one 

Downstream Products

• 60787-05-5 1-(4-methylpiperazin-l-yl)ethan-1-one 
• 60-35-5 acetamide 
• 76822-35-0 N-β-D-glucopyranosylthiourea 
• 23393-08-0 N-D-Glucopyranosyl-N'-allyl-thioharnstoff 
• 588-46-5 N-(phenylmethyl)acetamide 
• 76799-04-7 1-Benzyl-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-thiourea 
• 877-95-2 methyl-N-(benzyl-methyl)-formamide 
• 4109-40-4 N-<β-Phenyl-aethyl>-N'-β-D-glucosyl-thioharnstoff 
• 65562-43-8 5-benzylidene-3-β-D-glucopyranosyl-2-thioxo-thiazolidin-4-one 
• 18690-17-0 N-butyl-N'-(β-D-glucopyranosyl)thiourea 

Relevant academic research and scientific papers

N glucopyranosyl 5 aralkylidenerhodanines: Synthesis and antibacterial and antiviral activities

A series of N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-aralkylidenerhodanines was synthesized, and the acetyl groups were removed to give N-β-D-glucopyranosyl-5-aralkylidenerhodanines without cleavage of the rhodanine ring by means of acid hydrolysis. Alkaline hydrolysis with ammonia in methanol resulted in cleavage to N-glucosylthiourea, providing evidence for N-glycoside formation. A number of the rhodanine derivatives, especially those with nitro or chloro groups in the aromatic ring, showed antibacterial activity. N-β-D-Glucopyranosyl-5-(4-nitrobenzylidene)rhodanine showed antiviral activity by inhibition of viral RNA synthesis. Some effect on blood sugar levels also was observed with several rhodanines.