65594-96-9

Usage

Structure

Complex compound with a propionic acid backbone, phenyl, and isoindoline ring attachments.

Usage

Chemical intermediate in pharmaceutical and agrochemical synthesis.

Potential Applications

Medicine: Development of new drugs.
Agriculture: Production of pesticides or fertilizers.

Handling Requirements

Careful handling due to its complex structure and potential reactivity.
Thorough understanding of its chemical properties necessary for safe use.

InChI:InChI=1/C19H15NO6/c1-11(21)26-13-8-6-12(7-9-13)10-16(19(24)25)20-17(22)14-4-2-3-5-15(14)18(20)23/h2-9,16H,10H2,1H3,(H,24,25)/p-1/t16-/m1/s1

Upstream product

• 85-44-9 phthalic anhydride 
• 6636-22-2 O-acetyl-L-tyrosine 

Downstream Products

• 1583285-58-8 (Z)-4-(3-(diethoxyphosphoryl)-2-(1,3-dioxoisoindolin-2-yl)prop-1-en-1-yl)phenyl acetate 
• 1583285-59-9 C₂₃H₂₄NO₇P 
• 1583285-46-4 (S)-4-(3-diazo-3-(diethoxyphosphoryl)-2-(1,3-dioxoisoindolin-2-yl)propyl)phenyl acetate 

Relevant academic research and scientific papers

Trifluoroborane-catalyzed C-H functionalization/S-H insertion reaction: Construction of N,S-acetal quaternary centers

Abstract The trifluoroborane-catalyzed C-H functionalization/S-H insertion reaction of α-diazophosphonates with thiols has been developed. A plausible reaction mechanism has been proposed to understand the combined reaction. This process provides straightforward access to N,S-acetals containing quaternary centers in moderate to good yields and chemoselectivity.

Unexpected stereoselective synthesis of (Z)-β-alkenyl substituted β-amino phosphonates through β,γ-dihydrogen shift reaction catalyzed by a copper(I) complex and iodine [Cu(MeCN)4]PF 6/I2

A series of dialkyl a-diazophosphonates has been prepared from natural amino acids. The diazo decomposition of these diazophosphonate compounds with tetrakis(acetonitrile)copper(I) hexafluorophosphate/iodine, [Cu(MeCN) 4]PF6/I2, as catalyst has been investigated. It was found that the diazo decomposition of dialkyl a-diazophosphonates gave a mixture of β,γ-dihydrogen shift and 1,2-hydride migration products and afforded β-alk- enyl-substituted β-amino phosphonates with the Z configuration. The mechanism of this novel diazo decomposition process was discussed.