656-84-8

Upstream product

• 645-00-1 m-iodonitrobenzene 
• 116-14-3 polytetrafluoroethylene 
• 426-65-3 ethyl Pentafluoropropionate 
• 309-11-5 (pentafluoroethyl)benzene 

Downstream Products

• 2396-08-9 N,N-dimethyl-3-(pentafluoroethyl)aniline 
• 654-58-0 4-amino-6-pentafluoroethyl-benzene-1,3-disulfonic acid diamide 
• 729-84-0 3-Amino-1-pentafluorethyl-benzol-sulfonsaeure-⁽⁴⁾ 
• 729-83-9 3-Amino-4-sulfamoyl-1-pentafluorethyl-benzol 

Relevant academic research and scientific papers

CuI-Catalyzed Pentafluoroethylation of Aryl Iodides in the Presence of Tetrafluoroethylene and Cesium Fluoride: Determining the Route to the Key Pentafluoroethyl CuI Intermediate

The Cu(I)-catalyzed pentafluoroethylation of iodoarenes via the fluorocupration of tetrafluoroethylene (TFE) is disclosed. The active species, (phen)CuC2F5, was isolated and its molecular structure confirmed by a single-crystal X-ray diffraction analysis. The key to the successful suppression of the competing oligomerization of TFE is to refrain from stirring the reaction mixture. A mechanistic study clearly discarded the possibility that the catalytic reaction proceeds via a radical pathway.

KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER

The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject.

A Convenient Method for Catalytic Aromatic Pentafluoroethylation Using Potassium (Pentafluoroethyl)trimethoxyborate

A method for the copper-catalyzed pentafluoroethylation of aryl iodides using potassium (pentafluoroethyl)trimethoxyborate has been developed. The borate was found to be a convenient pentafluoroethyl source. In parallel, it was found that the solvent, as well as ligand, makes significant impact on the catalytic perfluoroalkylations.

Benzenedisulfonamides as anthelmintic agents

Haloalkyl benzenedisulfonamides are employed in the treatment of both mature and immature liver fluke infections. They are orally or parenterally administered to host animals in suitable compositions.