656-84-8

Basic information

• Product Name: Benzene, 1-nitro-3-(pentafluoroethyl)-
• CAS NO: 656-84-8
• Molecular Formula: C8H4F5NO2
• Molecular Weight: 241.117
• Mol File: 656-84-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-nitro-3-(pentafluoroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-nitro-3-(pentafluoroethyl)-(656-84-8)
• EPA Substance Registry System: Benzene, 1-nitro-3-(pentafluoroethyl)-(656-84-8)

Safety Data

• Hazardous Substances Data: 656-84-8(Hazardous Substances Data)

Upstream product

• 309-11-5 (pentafluoroethyl)benzene 
• 116-14-3 polytetrafluoroethylene 
• 645-00-1 m-iodonitrobenzene 
• 426-65-3 ethyl Pentafluoropropionate 

Downstream Products

• 2396-08-9 N,N-dimethyl-3-(pentafluoroethyl)aniline 
• 654-58-0 4-amino-6-pentafluoroethyl-benzene-1,3-disulfonic acid diamide 
• 729-84-0 3-Amino-1-pentafluorethyl-benzol-sulfonsaeure-⁽⁴⁾ 
• 729-83-9 3-Amino-4-sulfamoyl-1-pentafluorethyl-benzol 

Relevant articles and documents

CuI-Catalyzed Pentafluoroethylation of Aryl Iodides in the Presence of Tetrafluoroethylene and Cesium Fluoride: Determining the Route to the Key Pentafluoroethyl CuI Intermediate

The Cu(I)-catalyzed pentafluoroethylation of iodoarenes via the fluorocupration of tetrafluoroethylene (TFE) is disclosed. The active species, (phen)CuC2F5, was isolated and its molecular structure confirmed by a single-crystal X-ray diffraction analysis. The key to the successful suppression of the competing oligomerization of TFE is to refrain from stirring the reaction mixture. A mechanistic study clearly discarded the possibility that the catalytic reaction proceeds via a radical pathway.

A Convenient Method for Catalytic Aromatic Pentafluoroethylation Using Potassium (Pentafluoroethyl)trimethoxyborate

A method for the copper-catalyzed pentafluoroethylation of aryl iodides using potassium (pentafluoroethyl)trimethoxyborate has been developed. The borate was found to be a convenient pentafluoroethyl source. In parallel, it was found that the solvent, as well as ligand, makes significant impact on the catalytic perfluoroalkylations.