656227-67-7Relevant academic research and scientific papers
Facile Orthoester Formation in a Model Compound of the Taxol Oxetane: Are Biologically Active Epoxy Esters, Orthoesters, and Oxetanyl Esters Latent Electrophiles?
Giner, Jose-Luis,Faraldos, Juan A.
, p. 3613 - 3622 (2003)
A steroidal oxetanyl ester was synthesized in eight steps as a biomimetic model of taxol oxetane. The model compound was surprisingly reactive under acidic conditions, rearranging in the absence of H2O to a [2.2.1]-bicyclic orthoester. Both the
