656237-80-8

Upstream product

• 656237-79-5 4-chloro-N-2-{(1R)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}pyridine-2,3-diamine 
• 24358-62-1 (R)-1-(4-bromophenyl)ethylamine 
• 629655-23-8 2-chloro-3-nitro-4-hydroxypyridine 
• 656237-78-4 N-[(1R)-1-(4-bromophenyl)ethyl]-4-chloropyridine-2,3-diamine 
• 656237-77-3 N-[(1R)-1-(4-bromophenyl)ethyl]-4-chloro-3-nitropyridin-2-amine 

Downstream Products

• 656237-14-8 N-[4-chloro-2-({(1R)-1-[3'-fluoro-2'-(2-methyl-2H-tetraazol-5-yl)-1,1'-biphenyl-4-yl]ethyl}amino)pyridin-3-yl]isoxazole-5-carboxamide 

Relevant academic research and scientific papers

2,3-Diaminopyridine bradykinin B1 receptor antagonists

Bradykinin B1 receptor antagonists embody a potentially novel approach for the treatment of chronic pain and inflammation. A series of 2,3-diaminopyridine B1 antagonists was optimized to have sub-nanomolar affinity and good pharmacok