656238-49-2Relevant academic research and scientific papers
Total stereocontrolled synthesis of a novel pyrrolizidine iminosugar
De Angelis, Martina,Primitivo, Ludovica,Lizzio, Federica,Agostinelli, Sonia,Sappino, Carla,Ben Romdan, Ilaria,Bonanni, Luciano,D'Annibale, Andrea,Antonioletti, Roberto,Ricelli, Alessandra,Righi, Giuliana
, (2021/12/20)
Herein we describe a versatile approach to the pyrrolizidine alkaloids skeleton by tailoring our original strategy already used for the pyrrolidine iminosugars synthesis. The key steps are the regio- and stereoselective azidolysis of the suitable chiral v
Iridium-Catalyzed Regioselective Hydroalkynylation of Internal Alkenes Directed by an Oxime
Gao, Peng-Chao,Li, Bi-Jie,Wang, Zi-Xuan
supporting information, p. 9500 - 9504 (2021/12/14)
We report here an iridium-catalyzed hydroalkynylation of allylic alcohols protected by an oxime group. Catalytic alkynylation occurs exclusively at the distal position of the alkene. This method generates γ-alkynyl alcohol oximes directly from internal alkenes and terminal alkynes. The oxime group can be readily removed to afford a free alcohol, thus providing an indirect route for the catalytic hydroalkynylation of allylic alcohols.
Allylation of nitrosobenzene with pinacol allylboronates. A regioselective complement to peroxide oxidation
Kyne, Robert E.,Ryan, Michael C.,Kliman, Laura T.,Morken, James P.
supporting information; experimental part, p. 3796 - 3799 (2010/10/21)
Addition of nitrosobenzene to pinacol allylboronates leads to oxidation of the organoboron with concomitant rearrangement of the substrate alkene. This reaction appears to proceed by allylboration of the nitroso group in analogy to carbonyl and imine allylation reactions. Remarkably, the N-O bond is cleaved during the reaction such that simple alcohols are the final reaction product.
First stereoselective total synthesis of decarestrictine O via RCM protocol
Krishna, Palakodety Radha,Rao, T. Jagannadha
scheme or table, p. 4017 - 4019 (2010/08/07)
A convergent first stereoselective total synthesis of decarestrictine O via RCM protocol starting from 1,3-propanediol and propylene oxide is reported.
