488113-86-6

Upstream product

• 79568-67-5 (Z)-5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)pent-2-en-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 127665-77-4 (E)-5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)pent-2-en-1-ol 
• 127047-71-6 3-(tert-butyldiphenylsilyloxy)propan-1-ol 
• 112897-03-7 3-(tert-butyldiphenylsilyloxy)-1-propanal 
• 88159-03-9 5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)pent-2-yn-1-ol 
• 88158-68-3 4-(tert-butyldiphenylsilyloxy)-1-butyne 
• 656238-49-2 (E)-5-(tert-Butyl-diphenyl-silanyloxy)-pent-2-en-1-ol 

Downstream Products

• 79568-71-1 C₅₀H₆₈O₁₁Si₂ 
• 79568-70-0 C₃₉H₅₂O₈Si 
• 79568-65-3 (2S,3R)-2-Acetoxy-5-(tert-butyl-diphenyl-silanyloxy)-3-methyl-pentanoic acid 
• 79568-69-7 (2S,3R)-5-(tert-Butyl-diphenyl-silanyloxy)-2-hydroxy-3-methyl-pentanoic acid 
• 79568-68-6 (2S,3S)-3-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-oxirane-2-carboxylic acid 

Relevant academic research and scientific papers

Enantioselective synthesis of the C5-C23 segment of biselyngbyaside

Stereo and enantioselective synthesis of C5-C23 fragment of cytotoxic marine natural product biselyngbyaside is achieved using E-selective methyl lithium addition onto enyne, Crimmin's acetate aldol reaction, Sharpless asymmetric epoxidation, and Julia-Kocienski olefination as the key steps.

Total synthesis and biological evaluation of halipeptins A and D and analogues

The marine-derived halipeptins A (1a) and D (1d) and their analogues 3a, 3d and 4a, 4d were synthesized starting from building blocks 10, 13, 14a or 14d, 15, and 16. The first strategy for assembling the building blocks, involving a macrolactamization rea