656239-68-8

Upstream product

• 656239-62-2 3-(2-(4-hydroxy-phenyl)-pyridin-4-yl)-2-(pyridin-2-yl)-imidazo[1,2-a]pyridine 
• 106-93-4 ethylene dibromide 

Downstream Products

• 656240-06-1 2-(pyridin-2-yl)-3-[2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-pyridin-4-yl]-imidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS

This invention relates to novel 2-phenylpyridin-4-yl heterocyclyl derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.