656240-13-0

Basic information

• Product Name: Imidazo[1,2-a]pyridine, 7-methyl-3-[2-[4-[(1-methyl-1H-imidazol-4-yl)methoxy]phenyl]-4-pyridinyl ]-2-(6-methyl-2-pyridinyl)-
• CAS NO: 656240-13-0
• Molecular Formula: C30H26N6O
• Molecular Weight: 486.576
• Mol File: 656240-13-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-a]pyridine, 7-methyl-3-[2-[4-[(1-methyl-1H-imidazol-4-yl)methoxy]phenyl]-4-pyridinyl ]-2-(6-methyl-2-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine, 7-methyl-3-[2-[4-[(1-methyl-1H-imidazol-4-yl)methoxy]phenyl]-4-pyridinyl ]-2-(6-methyl-2-pyridinyl)-(656240-13-0)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine, 7-methyl-3-[2-[4-[(1-methyl-1H-imidazol-4-yl)methoxy]phenyl]-4-pyridinyl ]-2-(6-methyl-2-pyridinyl)-(656240-13-0)

Safety Data

• Hazardous Substances Data: 656240-13-0(Hazardous Substances Data)

Upstream product

• 17289-25-7 hydroxymethylene-4 N-methylimidazole 
• 656239-66-6 7-methyl-3-(2-(4-hydroxy-phenyl)-pyridin-4-yl)-2-(6-methyl-pyridin-2-yl)-imidazo[1,2-a]pyridine 
• 17289-30-4 4-(chloromethyl)-1-methyl-1H-imidazole hydrochloride 

Relevant articles and documents

COMPOUNDS

The invention relates to novel imidazopyridine derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.