656257-45-3

Basic information

• Product Name: 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester
• Synonyms: 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester;1-Ethyl-4-[4-(4.4.5.5-tetraMethyl-1.3.2-dioxaborolan-2-yl)phenyl]piperazine;4-(4-Ethylpiperazino)phenylboronic Acid Pinacol Ester;4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpicolester
• CAS NO: 656257-45-3
• Molecular Formula: C₁₈H₂₉BN₂O₂
• Molecular Weight: 316.25
• Mol File: 656257-45-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 469.717°C at 760 mmHg
• Flash Point: 237.876°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester(656257-45-3)
• EPA Substance Registry System: 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester(656257-45-3)

Safety Data

• Hazardous Substances Data: 656257-45-3(Hazardous Substances Data)

Usage

Uses

1-Ethyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine

InChI:InChI=1/C18H31BN2O3/c1-6-20-11-13-21(14-12-20)16-9-7-15(8-10-16)19(23)24-18(4,5)17(2,3)22/h7-10,22-23H,6,11-14H2,1-5H3

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 656257-43-1 1-(4-bromophenyl)-4-ethylpiperazine 
• 66698-28-0 1-(4-bromophenyl)piperazine 
• 5308-25-8 4-ethylpiperazine 
• 589-87-7 1,4-bromoiodobenzene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Downstream Products

• 1247003-79-7 (1R,2S)-2-(3-(4-(4-ethylpiperazin-1-yl)phenyl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one 

Relevant articles and documents

CHLOROBENZENE SUBSTITUTED AZAARYL COMPOUNDS

The invention provides a series of chlorobenzene substituted azaaryl compounds having activity in inhibiting cancer cell growth and low toxicity to normal cells. Particularly, the compounds of the invention have stronger inhibition effect on bladder cance

COMPOUNDS

The invention relates to novel aminothiazole derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.