656257-67-9

Basic information

• Product Name: 4-Pyridinecarboxaldehyde, 2-[4-(ethylsulfonyl)phenyl]-
• CAS NO: 656257-67-9
• Molecular Formula: C14H13NO3S
• Molecular Weight: 275.328
• Mol File: 656257-67-9.mol

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxaldehyde, 2-[4-(ethylsulfonyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxaldehyde, 2-[4-(ethylsulfonyl)phenyl]-(656257-67-9)
• EPA Substance Registry System: 4-Pyridinecarboxaldehyde, 2-[4-(ethylsulfonyl)phenyl]-(656257-67-9)

Safety Data

• Hazardous Substances Data: 656257-67-9(Hazardous Substances Data)

Upstream product

• 101066-61-9 2-chloropyridine-4-carbaldehyde 
• 352530-24-6 4-(ethylsulfonyl)phenylboronic acid 

Downstream Products

• 656257-66-8 [(2-(4-ethanesulfonylphenyl)-pyridin-4-yl)-(phenylamino)-methyl]-phosphonic acid diphenylester 

Relevant articles and documents

2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS

This invention relates to novel 2-phenylpyridin-4-yl heterocyclyl derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.