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10-(4'-chlorophenyl)-3-methylflavin is a synthetic flavin derivative characterized by the presence of a 4'-chlorophenyl group at the 10th position and a methyl group at the 3rd position. Flavins are a class of heterocyclic compounds that play a crucial role in various biological processes, such as cellular respiration and photosynthesis, due to their ability to participate in redox reactions. This specific compound, with its unique structural modifications, may exhibit altered properties compared to natural flavins, potentially affecting its reactivity, stability, and interaction with other molecules. The chlorophenyl group may introduce new electronic and steric effects, while the methyl group could influence the compound's lipophilicity and solubility. These modifications can be significant in the context of drug design, where such alterations can lead to improved pharmacokinetics or enhanced binding affinity to target proteins.

65626-87-1

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65626-87-1 Usage

Chemical group

Flavin group

Type of compound

Flavoprotein

Molecular weight

366.79 g/mol

4'-chlorophenyl group

Attached to the 10th carbon in the flavin ring

Methyl group

At the 3rd position

Antioxidant properties

Helps neutralize harmful free radicals

Anti-inflammatory properties

Reduces inflammation in the body

Enzymatic reactions

Involved in various enzymatic reactions

Research applications

Used as a probe to study the binding of flavin cofactors to proteins and their redox properties.

Check Digit Verification of cas no

The CAS Registry Mumber 65626-87-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,2 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65626-87:
(7*6)+(6*5)+(5*6)+(4*2)+(3*6)+(2*8)+(1*7)=151
151 % 10 = 1
So 65626-87-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H11ClN4O2/c1-21-16(23)14-15(20-17(21)24)22(11-8-6-10(18)7-9-11)13-5-3-2-4-12(13)19-14/h2-9H,1H3

65626-87-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 10-(4'-Chlorophenyl)-3-methylisoalloxazine

1.2 Other means of identification

Product number -
Other names 10-(4-chloro-phenyl)-3-methyl-10H-benzo[g]pteridine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65626-87-1 SDS

65626-87-1Relevant academic research and scientific papers

A new and improved N-3 alkylation of 10-substituted isoalloxazines using 1,8-diazabicyclo[5.4.0]undec-7-ene in benzene

Geetanjali,Singh, Ram,Chauhan

, p. 613 - 620 (2007/10/03)

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been identified as a remarkable base for the alkylation at N-3 position of 10-substituted isoalloxazines with alkyl halides in dry benzene.

Synthesis and Characterization of Water-Soluble and Photolabile 10-Arylisoalloxazines: Tools for Studying the Mechanism of Action of Flavin-Type Antimalarials

Kirsch, Peer,Schoenleben-Janas, Annette,Schirmer, R. Heiner

, p. 1275 - 1282 (2007/10/02)

Isoalloxazine derivatives such as 1a-d are promising antimalarial agents which act as inhibitors of the antioxidant enzyme glutathione reductase and possibly of other proteins.The molecular mechanism of the pharmacological effects has not been studied in detail because compounds 1a-d are poorly soluble in aqueous solutions of physiological pH.In the present study we introduce two new types of isoalloxazine derivatives with improved solubility properties.The 10-aryl-3-carboxymethylisoalloxazines 2a-d, and the isomeric 3-methyl-10-(N-methylpyridiniumyl)isoalloxazine salts 3 and 4.In addition, for the purpose of photoaffinity labeling experiments, the 10-aryl-8-azido-3-methylisoalloxazine 5 was designed.The syntheses and characterizations of these new flavins as well as an alternative synthetic approach to the known antimalarials 1a-d are described. - Keywords: Flavins/Isoalloxazines/Arylisoalloxazines/Malaria/Antimalarials/Glutathione reductase inhibitors/Photoaffinity labels

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