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Tetrahydro-1,2-dithiin is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

505-20-4

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505-20-4 Usage

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 655, 1973 DOI: 10.1016/S0040-4039(00)72425-7

Check Digit Verification of cas no

The CAS Registry Mumber 505-20-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 505-20:
(5*5)+(4*0)+(3*5)+(2*2)+(1*0)=44
44 % 10 = 4
So 505-20-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H8S2/c1-2-4-6-5-3-1/h1-4H2

505-20-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-dithiane

1.2 Other means of identification

Product number -
Other names 1,2-Dithiane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:505-20-4 SDS

505-20-4Relevant academic research and scientific papers

Synthesis of common-sized heterocyclic compounds by intramolecular cyclization over halide cluster catalysts

Nagashima, Sayoko,Sasaki, Tomoaki,Kamiguchi, Satoshi,Chihara, Teiji

supporting information, p. 764 - 766 (2015/06/22)

Five- to seven-membered common-sized heterocyclic compounds containing an oxygen, sulfur, or nitrogen were synthesized by the intramolecular condensation of α,ω-hydroxy, mercapto, or amino alkanes, respectively, over halide cluster complexes as a thermally stable molecular solid weak acid catalyst in the gas phase at temperatures ≥150 °C. From ω- mercapto and ω-amino alcohols, cyclic sulfides and amines were obtained, respectively. These unimolecular reactions are thermodynamically and kinetically favored.

The first direct oxidative conversion of a selenol to a stable selenenic acid: Experimental demonstration of three processes included in the catalytic cycle of glutathione peroxidase

Goto, Kei,Nagahama, Michiko,Mizushima, Tadashi,Shimada, Keiichi,Kawashima, Takayuki,Okazaki, Renji

, p. 3569 - 3572 (2007/10/03)

(matrix presented) A stable selenenic acid was synthesized by direct oxidation of a selenol bearing a novel bowl-type substituent with H2O2, and its structure was established by X-ray crystallographic analysis. Selenenyl sulfides obt

AZOLE INHIBITORS OF CYTOKINE PRODUCTION

-

, (2008/06/13)

Compounds having the formula are useful for treating diseases that are prevented by or ameliorated with Interleukin-2, Interleukin-4, or Interleukin-5 production inhibitors.

Reduction of thiokols in the system hydrazine hydrate-base as a new route to alkanedithiols

Alekminskaya,Russavskaya,Korchevin,Deryagina,Trofimov

, p. 732 - 737 (2007/10/03)

A new procedure for preparative synthesis of alkanedithiols from simple commercially available products is based on reduction of the S-S bond in appropriate polyalkylene disulfides (thiokols) in the system hydrazine hydrate-base. Thiokols were prepared by reaction of dihaloalkanes with Na2S2 or K2S2 generated from elemental sulfur and alkali in aqueous hydrazine hydrate. Reaction of 1,2-dibromocyclohexane with sodium or potassium disulfide yields bis(2-bromocyclohexyl) sulfide as the only product.

Reduction of thiocols to alkanepolythiols with benzeneselenol

Shilkina,Papernaya,Deryagina

, p. 263 - 265 (2007/10/03)

Heating of benzeneselenol with polymethylene disulfides to 40-120°C results in formation of the corresponding alkanedithiols or alkanetrithiols and diphenyl diselenide. Poly(tetramethylene disulfide) reacts with benzeneselenol to give 1,2-dithiane and diphenyl diselenide. A radical mechanism of this reaction is discussed.

Degenerate intermolecular thiolate-disulfide interchange involving cyclic five-membered disulfides is faster by ~103 than that involving six- or seven-membered disulfides

Singh, Rajeeva,Whitesides, George M.

, p. 6304 - 6309 (2007/10/02)

The rate constants for degenerate intermolecular thiolate-disulfide interchange involving 1,2-dithiolane (S(CH2)3S) are higher than those involving 1,2-dithiane (S(CH2)4S) by a factor of ~650 in mixtures of DMSO-d6 and D2O. The extrapolated rate constant for 1,2-dithiolane in DMSO-d6 is fast (k ~ 108 M-1 s-1). The rate constants for cyclic six- and seven-membered disulfides are similar to those for acyclic disulfides. Rate constants for self-exchange were measured by dynamic 1H NMR line-shape analysis. The evolutionary selection of lipoamide as the cofactor in 2-oxo acid dehydrogenases may reflect the fast rate of ring opening of the dithiolane ring by nucleophiles.

Substituent and Steric Effects of Flavin Models in the Reactions of N-Benzyl-1,4-dihydronicotinamide, Butane-1,4-dithiol, Phenylhydrazine, and Nitroethane

Yano, Yumihiko,Nakazato, Michiaki,Ohya, Eiichi

, p. 77 - 82 (2007/10/02)

Reactivities of 3-methyl-10-phenyl-8-substituted-, 3-methyl-10-(p-substituted phenyl)-, and 3,6-dimethyl-10-phenylisoalloxazines have been kinetically investigated for oxidations of N-benzyl-1,4-dihydronicotinamide, HS(CH2)4SH, PhNHNH2, and EtNO2 in EtOH containing diazabicycloundecence as a base or in aqueous solution under anaerobic conditions.Substituent effects and the steric hindrance of the 6-methyl group are discussed in connection with the reaction mechanisms.

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