65628-41-3Relevant academic research and scientific papers
Organocatalytic γ′[C(sp 3)-H] Functionalization of Ynones: An Unusual Approach for the Cyclopentannulation of Benzothiophenes
Grover, Jagdeep,Raghu, Moluguri,Hazra, Raju,Mondal, Atanu,Ramasastry
, p. 1462 - 1470 (2018/01/27)
An efficient organocatalytic approach for the cyclopenta[ b ]annulation of benzothiophenes via γ′[C(sp 3)-H] functionalization of ynones is described. Nucleophilic addition of an organophosphine to the designed ynones generates heteroaryl-based ortho -quinodimethanes (oQDMs), which undergo carbocyclization to provide a variety of cyclopenta-fused benzothiophenes. This approach also constitutes an unusual organophosphine-catalyzed intramolecular hydroalkylation of ynones.
Efficient 1,2-addition of aryl- and alkenylboronic acids to aldehydes catalyzed by the palladium/thioether-imidazolinium chloride system
Kuriyama, Masami,Shimazawa, Rumiko,Shirai, Ryuichi
, p. 1597 - 1600 (2008/09/17)
(Chemical Equation Presented) The high level of catalyst performance was attainable in the palladium-catalyzed 1,2-addition of aryl-, heteroaryl-, and alkenylboronic acids to aromatic, heteroaromatic, and aliphatic aldehydes using thioether-imidazolinium chloride L5 as a heterobidentate carbene ligand precursor.
Palladium-catalyzed 1,2-addition of potassium aryl- and alkenyltrifluoroborates to aldehydes using thioether-imidazolinium carbene ligands
Kuriyama, Masami,Shimazawa, Rumiko,Enomoto, Terumichi,Shirai, Ryuichi
, p. 6939 - 6942 (2008/12/22)
(Chemical Equation Presented) Palladium-catalyzed 1,2-addition of potassium aryl- and alkenyltrifluoroborates to aldehydes using thioether- imidazolinium carbene ligands proceeded readily under aqueous conditions. This process tolerated a diverse range of potassium trifluoroborate salts and aldehydes, giving a variety of carbinol derivatives with good to excellent yields.
New imidazole anti-fungal agents derived from benzothiophene. Part II
Moreno-Manas, Marcial,Cuberes, Ma. Rosa,Palacin, Celia,Raga, Manuel,Castello, Josep M.,Ortiz, Jose A.
, p. 477 - 482 (2007/10/02)
1-thienyl)methyl>-1H-imidazoles 22, 1-thien-3-yl)(thienyl)methyl>-1H-imidazoles 25 and 1-thien-3-yl)methyl>-1H-imidazoles 28 have been synthesized and tested for anti-fungal activity.All compounds showed good activity against a broad spectrum of fungi (yeasts, dermatophytes).
