65655-83-6Relevant academic research and scientific papers
Preparation of thiazolidin-4-one derivatives using ZnO–NiO–NiFe2O4 nano-composite system
Lashkari, Mojtaba,Ghashang, Majid
, p. 589 - 597 (2020/10/15)
The hydrothermal synthesis of ZnO–NiO–NiFe2O4 nano-composite is reported. The sample was utilized to characterize via XRD, FE-SEM, EDS, FT-IR, UV–Vis, and BET techniques. The sample consisted of three different phases as ZnO (hexagonal), NiO (cubic), and NiFe2O4 (cubic) with the average particle size as 34?nm and specific surface area, average pore diameter, and pore volume as 64.35?m2?g?1, 13.02?nm, and 0.201?cm3?g?1, respectively. Catalytic behavior of the nano-composite was investigated on the synthesis of thiazolidin-4-one derivatives under thermal and ultrasonic irradiation condition. Our results show that the catalytic activity of ZnO–NiO–NiFe2O4 nano-composite is much higher than ZnO, NiO, and NiFe2O4 metal oxides. All products were prepared in high yields with short reaction times. In addition, the catalyst was recovered for at least five times.
Silica chloride (SiO2-Cl) catalyzed one pot synthesis of 2,3-disubstituted-thiazolidin-4-one
Gokhale, Kunal M.,Telvekar, Vikas N.
supporting information, p. 1396 - 1403 (2020/03/31)
In this paper, we report one-pot, three-component cyclo condensation of an aldehyde, an amine and thioglycolic acid to form 2,3-disubstituted-thiazolidin-4-one by using supported protic acid (Silica Chloride: SiO2-Cl) catalyst. The catalyst SiO2-Cl is compatible with a variety of aldehydes (aryl/heteroaryl) and the aromatic amines affording 2,3-disubstituted-thiazolidin-4-one analogs in 72–89% yields. Moreover, the supported catalyst was recycled several times without significant loss of catalytical activity.
Tromethamine organocatalyzed efficient tandem-multicomponent synthesis of new thiazolyl-4-thiazolidinones in aqueous medium
Bhosle, Manisha R.,Kharote, Sayali A.,Bondle, Giribala M.,Mali, Jyotirling R.
supporting information, p. 1286 - 1300 (2019/04/30)
The catalytic potential of tris(hydroxymethyl)aminomethane (Tromethamine) has been assessed for the one pot three component tandem reaction involving a thiazolylmethoxy phenyl/aromatic carboxaldehyde, substituted amines and thioglycolic acid to form new t
Graphene oxide catalyzed C-N/C-S/[3+2] cyclization cascade for green synthesis of thiazolidinone in water
Mahata, Suhasini,Sahu, Anjumala,Shukla, Prashant,Rai, Ankita,Singh, Manorama,Rai, Vijai K.
, p. 665 - 672 (2018/07/14)
In this paper, first graphene oxide catalyzed one-pot three-component green synthesis of 1,3- thiazolidin-4-one using amine, aldehyde and mercapto acetic acid in water has been reported. The reaction is affected via sequential C-N and C-S bond formation a
A catalysis study of mesoporous MCM-41 supported Schiff base and CuSO4·5H2O in a highly regioselective synthesis of 4-thiazolidinone derivatives from cyclocondensation of mercaptoacetic acid
Pang, Hai-Xia,Hui, Yong-Hai,Fan, Kui,Xing, Xue-Jian,Wu, Yang,Yang, Jing-Hui,Shi, Wei,Xie, Zheng-Feng
, p. 335 - 339 (2016/03/16)
Mesoporous MCM-41 supported Schiff base and CuSO4·5H2O shows high catalytic activity in the cyclocondensation of mercaptoacetic acid with imines (or aldehydes and amines) to afford pharmaceutically important thiazolidinone derivatives. The catalytic reactions involving two-components or three-components afforded the desired product in high yields (up to 98% and 99%). Moreover, the catalyst works well with respect to recyclability, giving the product in 85% and 83% yields after recycling six times.
Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents
Subhedar, Dnyaneshwar D.,Shaikh, Mubarak H.,Arkile, Manisha A.,Yeware, Amar,Sarkar, Dhiman,Shingate, Bapurao B.
supporting information, p. 1704 - 1708 (2016/07/27)
We have developed, highly efficient, one-pot, solvent-free, [Et3NH][HSO4] catalyzed multicomponent reaction protocol for the synthesis of 1,3-thiazolidin-4-ones in excellent yields. For the first time, the 1,3-thiazolidin-4-ones were evaluated in vitro for their antimycobacterial activity against Mycobacterium tuberculosis dormant MTB H37Ra and Mycobacterium bovis BCG strains. Among the synthesized basic 1,3-thiazolidin-4-ones, particularly the compounds 4c, 4d, 4e, 4f, 4h, 4i and 4j displays promising antitubercular activity along with no significant cytotoxicity against the cell lines MCF-7, A549 and HCT-116.
Preparation of novel 2-(2-oxo-2 H-chromen-4-yl)-3-arylthiazolidin-4-one derivatives using an efficient ionic liquid catalyst
Ghashang, Majid,Taghrir, Hadi,Biregan, Mohammad Najafi,Heydari, Negar,Azimi, Fateme
, p. 61 - 69 (2016/02/12)
An eco-friendly procedure for synthesis of 2-(2-oxo-2H-chromen-4-yl)-3-arylthiazolidin-4-one derivatives by three-component reaction of 2-oxo-2H-chromene-4-carbaldehydes, aromatic amines and thioglycolic acid, with tetramethylbutane-1,4-diammonium acetate
Pd nanoparticles: an efficient catalyst for the solvent-free synthesis of 2,3-disubstituted-4-thiazolidinones
Harale, Rajkumar R.,Shitre, Praveen V.,Sathe, Bhaskar R.,Shingare, Murlidhar S.
, p. 6695 - 6703 (2016/07/12)
Abstract: Palladium nanoparticles (Pd NPs: ~5-nm diameter) catalysed an efficient, solvent-free protocol for the cyclocondensation reaction of the aldehydes, anilines and mercaptoacetic acid has been developed. This method offers a rapid, relatively economical and ecofriendly protocol for the synthesis of 2,3-disubstituted-4-thiazolidinones for the first time. Moreover, the catalyst can also be easily recovered and recycled with no loss of catalytic activity. Graphical Abstract: [Figure not available: see fulltext.]
β-Cyclodextrin-SO3H-catalyzed facile and highly efficient synthesis of 4-thiazolidinones under solvent free conditions
Chaudhari, Mahendra A.,Gujar, Jitendra B.,Kawade, Deepak S.,Shinde, Pravin V.,Shingare, Murlidhar S.
, p. 10027 - 10035 (2016/01/12)
A one-pot, multi-component, green, and highly efficient procedure has been developed for synthesis of 4-thiazolidinones. Use of β-cyclodextrin-SO3H as an ecofriendly and recyclable catalyst resulted in excellent yields under solvent-free condit
One-pot rapid synthesis of thiazole-substituted pyrazolyl-4-thiazolidinones mediated by diisopropylethylammonium acetate
Khillare, Lalit D.,Bhosle, Manisha R.,Deshmukh, Amarsinh R.,Mane, Ramrao A.
, p. 8955 - 8964 (2015/02/19)
A convenient one-pot, rapid and scalable synthetic protocol has been developed for recently reported anti-inflammatory agents, thiazole-substituted pyrazolyl-4-thiazolidinones. Quantitative multicomponent cyclocondensation of 3-(4-methyl-2-substituted thi
