656833-28-2Relevant academic research and scientific papers
3-AMINO-2-HRYDROXYALKANOIC ACIDS AND THEIR PRODRUGS
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Page 16, (2010/02/06)
Compounds having the formula are useful for treating conditions which arise from or are exacerbated by angiogenesis. Also disclosed are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting a
3-Amino-2-hydroxyalkanoic acids and their prodrugs
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Page/Page column 8, (2010/02/07)
Compounds having the formula are useful for treating conditions which arise from or are exacerbated by angiogenesis. Also disclosed are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting a
3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2
Sheppard, George S.,Wang, Jieyi,Kawai, Megumi,BaMaung, Nwe Y.,Craig, Richard A.,Erickson, Scott A.,Lynch, Linda,Patel, Jyoti,Yang, Fan,Searle, Xenia B.,Lou, Pingping,Park, Chang,Kim, Ki H.,Henkin, Jack,Lesniewski, Richard
, p. 865 - 868 (2007/10/03)
Substituted 3-amino-2-hydroxyamides and related hydroxyamides and acylhydrazines were identified as inhibitors of human methionine aminopeptidase-2 (MetAP2). Examination of substituents through parallel synthesis and iterative structure-based design allow
Hydrazide and alkoxyamide angiogenesis inhibitors
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, (2008/06/13)
Compounds having the formula are methionine aminopeptidase type 2 (MetAP2) inhibitors and are useful for inhibiting angiogenesis. Also disclosed are MetAP2-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
