656833-35-1Relevant academic research and scientific papers
Design and synthesis of β-amino-α-hydroxy amide derivatives as inhibitors of MetAP2 and HUVEC growth
Sendzik, Martin,Janc, James W.,Cabuslay, Ronnel,Honigberg, Lee,Mackman, Richard L.,Magill, Catherine,Squires, Neil,Waldeck, Nancy
, p. 3181 - 3184 (2007/10/03)
The rational design and synthesis of β-amino-α-hydroxy amide derivatives as reversible inhibitors of methionine aminopeptidase-2 (MetAP2) with anti-proliferative activity against human umbilical vein endothelial cells (HUVECs) is described.
3-AMINO-2-HRYDROXYALKANOIC ACIDS AND THEIR PRODRUGS
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Page 24, (2010/02/06)
Compounds having the formula are useful for treating conditions which arise from or are exacerbated by angiogenesis. Also disclosed are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting a
3-Amino-2-hydroxyalkanoic acids and their prodrugs
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Page/Page column 11, (2010/02/07)
Compounds having the formula are useful for treating conditions which arise from or are exacerbated by angiogenesis. Also disclosed are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting a
