65686-13-7

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-CHLORO-PHENOXY)ETHYL METHYL AMINE is used as an intermediate for the synthesis of active pharmaceutical ingredients, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2-(4-CHLORO-PHENOXY)ETHYL METHYL AMINE is used as a starting material in the synthesis of agrochemicals, playing a crucial role in the creation of products that enhance crop protection and agricultural productivity.
Used in Research and Development:
2-(4-CHLORO-PHENOXY)ETHYL METHYL AMINE is employed in research and development projects within the pharmaceutical and agricultural industries, facilitating the exploration of new chemical pathways and the discovery of innovative applications for this versatile compound.

InChI:InChI=1/C9H12ClNO/c1-11-6-7-12-9-4-2-8(10)3-5-9/h2-5,11H,6-7H2,1H3/p+1

Upstream product

• 53542-78-2 O-methanesulfonyl-2-(4-chlorophenoxy)ethanol 
• 74-89-5 methylamine 
• 1892-43-9 2-(4-chlorophenoxy)ethanol 

Downstream Products

• 58929-56-9 [2-(4-Chloro-phenoxy)-ethyl]-{2-[2-(2-{[2-(4-chloro-phenoxy)-ethyl]-methyl-amino}-ethoxy)-ethoxy]-ethyl}-methyl-amine 
• 224178-05-6 tert-Butyl 2-(N-(2-(4-Chlorophenoxy)ethyl)-N-methylsulfamoylmethyl)-3-methylbutanoate 
• 424822-04-8 (R)-2-((R)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-3-methyl-butane-1-sulfonic acid [2-(4-chloro-phenoxy)-ethyl]-methyl-amide 
• 224178-20-5 2-(N-(2-(4-Chlorophenoxy)ethyl)-N-methylsulfamoyl-methyl)-3-methylbutanoic Acid 
• 424822-02-6 (R)-2-({[2-(4-Chloro-phenoxy)-ethyl]-methyl-sulfamoyl}-methyl)-3-methyl-butyric acid 

Relevant academic research and scientific papers

Convenient Continuous Flow Synthesis of N-Methyl Secondary Amines from Alkyl Mesylates and Epoxides

The first continuous flow process was developed to synthesize N-methyl secondary amines from alkyl mesylates and epoxides via a nucleophilic substitution using aqueous methylamine. A variety of N-methyl secondary amines were produced in good to excellent yields, including a number of bioactive compounds or their precursors. Up to 10.6 g (88% yield) of an N-methyl secondary amine was produced in 140 min process time. The amination procedure included an in-line workup, and the starting mesylate material was also produced in continuous flow from the corresponding alcohol. Finally, an in-line process combining the mesylate synthesis and nucleophilic substitution was developed.