65686-86-4 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-CHLORO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE is used as a building block for the synthesis of active pharmaceutical ingredients. Its presence in the molecular structure of certain drugs can enhance their properties, such as bioavailability and metabolic stability, due to the introduction of the trifluoroethylamine group.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-CHLORO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE is utilized as a key component in the creation of various agrochemicals. The trifluoromethylamine derivative contributes to the development of compounds with improved performance characteristics, such as increased effectiveness and selectivity in pest control.
Used in Chemical Research and Development:
1-(4-CHLORO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE also serves as a reagent in chemical research and development. Its unique properties make it a useful tool for exploring new chemical reactions and synthesizing novel compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 65686-86-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,8 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65686-86:
(7*6)+(6*5)+(5*6)+(4*8)+(3*6)+(2*8)+(1*6)=174
174 % 10 = 4
So 65686-86-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClF3N/c9-6-3-1-5(2-4-6)7(13)8(10,11)12/h1-4,7H,13H2
65686-86-4Relevant academic research and scientific papers
Silver-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides: a facile stereoselective synthesis of CF3-substituted heterocycles
Zhang, Xue,Wang, Xin,Gao, Yuelei,Xu, Xianxiu
supporting information, p. 2427 - 2430 (2017/03/01)
An Ag-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides with polar double bonds has been developed for the facile access to trifluoromethylated oxazolines, imidazolines and pyrrolines under mild conditions. The practicality of this chemistry is demonstrated by the gram-scale synthesis of oxazolines with excellent yields and facile transformations of the formed oxazolines to trifluoromethylated β-amino alcohols in quantitative yields.
Aryltrifluoroethylamines
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, (2008/06/13)
Certain arylmethyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.
