65689-60-3

Basic information

• Product Name: Benzeneacetic acid, 2-amino-3-(4-chlorobenzoyl)-a-(methylthio)-, ethyl ester
• CAS NO: 65689-60-3
• Molecular Formula: C18H18ClNO3S
• Molecular Weight: 363.865
• Mol File: 65689-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 2-amino-3-(4-chlorobenzoyl)-a-(methylthio)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2-amino-3-(4-chlorobenzoyl)-a-(methylthio)-, ethyl ester(65689-60-3)
• EPA Substance Registry System: Benzeneacetic acid, 2-amino-3-(4-chlorobenzoyl)-a-(methylthio)-, ethyl ester(65689-60-3)

Safety Data

• Hazardous Substances Data: 65689-60-3(Hazardous Substances Data)

Upstream product

• 2894-51-1 2-amino-4'-chlorobenzophenone 

Downstream Products

• 61085-31-2 7-(4-chlorobenzoyl)-3-methylthioindolin-2-one 
• 91714-39-5 7-(4-chlorobenzoyl)-1,3-dihydro-5-nitro-2H-indol-2-one 
• 91714-40-8 5-amino-7-(4-chlorobenzoyl)-1,3-dihydro-2H-indol-2-one 
• 61941-62-6 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid, sodium salt 
• 61112-01-4 7-(p-chlorobenzoyl)-indolin-2-one 

Relevant articles and documents

Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues

A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been synthesized and evaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting activity. Several derivatives including 4'-chloro, 4'-bromo and 5-chloro, 4'-bromo were more potent than indomethacin in these assays.