65699-13-0

Basic information

• Product Name: Acetamide, 2-amino-N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarb onyl)-1H-1,2,4-triazol-5-yl]methyl]-
• CAS NO: 65699-13-0
• Molecular Formula: C23H22Cl2N6O3
• Molecular Weight: 501.372
• Mol File: 65699-13-0.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-amino-N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarb onyl)-1H-1,2,4-triazol-5-yl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-amino-N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarb onyl)-1H-1,2,4-triazol-5-yl]methyl]-(65699-13-0)
• EPA Substance Registry System: Acetamide, 2-amino-N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarb onyl)-1H-1,2,4-triazol-5-yl]methyl]-(65699-13-0)

Safety Data

• Hazardous Substances Data: 65699-13-0(Hazardous Substances Data)

Upstream product

• 65699-03-8 C₁₉H₁₈Cl₂N₄O₂ 
• 65698-98-8 C₁₇H₁₅Cl₂N₃O₃ 
• 65699-08-3 1-{1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-[(N,N-phthaloyl-glycylamino)-methyl]-1H-[1,2,4]triazole-3-carbonyl}-pyrrolidine 

Relevant articles and documents

Synthesis and biological activity of (3,5-disubstituted-1H-1,2,4-triazol-1-yl)benzophenone derivatives (1)

The synthesis of (5-acylaminomethyl-3-carbamoyl-1H-1,2,4-triazol-1-yl)benzophenone derivatives is described. Acylation of the key intermediate, 1-benzoylphenylazo-1-aminoacetamide followed by cyclization in the presence of acid afforded 1H-1,2,4-triazole derivates. These compounds were evaluated for their central nervous system (CNS) activity. Some of these compounds exhibited high activities in anti-pentylene tetrazole and rotarod test in mice orally administered.

Triazolylphenyl ketone derivatives and production thereof

Triazolyl ketone derivatives of the formula: STR1 (wherein R represents lower alkoxy or the group STR2 R4 and R5 each represents hydrogen, lower alkyl, STR3 represents hetero ring selected from pyrrolidino, piperidino, and morpholino; R1 represents halogen or nitro; R2 represents hydrogen or lower alkyl; R3 represents lower alkyl, phenyl, or the group STR4 R6 represents hydrogen, lower alkyl, or benzyl; R7 and R8 each represents hydrogen, lower alkyl, or STR5 represents hetero ring selected from pyrrolidino, piperidino, and morpholino; and Ar represents phenyl, o-halogenophenyl, or 2-pyridyl) and their pharmaceutically acceptable acid addition salts, being useful as anxiolytics, hypnotics, anticonvulsants, muscle relaxants, or their synthetic intermediates, are prepared by several routes.