657-81-8Relevant academic research and scientific papers
INHIBITORS OF TYROSINE KINASES AND USES THEREOF
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Page/Page column 104, (2008/06/13)
Disclosed herein are compounds that inhibit the activity of particular tyrosine kinases. Methods for the preparation of such compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the compounds disclosed, alone or in combination with other therapeutic agents, for the treatment of tyrosine kinase-rnediated diseases or conditions or tyrosine, kinase-dependent diseases or conditions are provided.
Reactions of aryltetrachlorophosphoranes with sodium dithionite and sulfuryl chloride
Mitrasov,Anisimova,Kormachev
, p. 765 - 766 (2007/10/03)
Reaction of aryltetrachlorophosphoranes with sodium dithionite or sulfuryl chloride leads to dichloroanhydrides of arylphosphonic acids in high yields. 1996 MAEe cyrillic signK Hayκa/Interperiodica Publishing.
Effect of para Substituents on Decomposition Rates of 2-(N,N'-Dimethylamino)ethyl Phenyl Phenylphosphonates
Manninen, P. Antti
, p. 635 - 640 (2007/10/02)
Spontaneous decomposition of nineteen of the title phosphonates to their 1,1,4,4-tetramethylpiperazinium salts was followed in 50 percent aqueous ethanol at different temperatures.The effect of substituents of the phenyl group on reaction rates was about
SYNTHESIS OF PHOSPHONIC DICHLORIDES AND CORRELATION OF THEIR P-31 CHEMICAL SHIFTS
Grabiak, Raymond C.,Miles, James A.,Schwenzer, Gretchen M.
, p. 197 - 202 (2007/10/02)
Various mono-substituted diethyl arylphosphonates were prepared in good yield by treatment of aryl bromides or iodides with triethyl phosphite in the presence of NiCl2 or alternatively, addition of the aryl grignard reagent to diethyl phosphorochloridate.
