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N-(tetrahydropyran-4-yl)-4-(4-{2-tert-butyl-5-[6-methyl-pyridin-2-yl]-1H-imidazol-4-yl}-pyridin-2-yl)-benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

657399-24-1

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657399-24-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 657399-24-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,7,3,9 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 657399-24:
(8*6)+(7*5)+(6*7)+(5*3)+(4*9)+(3*9)+(2*2)+(1*4)=211
211 % 10 = 1
So 657399-24-1 is a valid CAS Registry Number.

657399-24-1Downstream Products

657399-24-1Relevant academic research and scientific papers

2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS

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Page 94-95, (2010/02/06)

This invention relates to novel 2-phenylpyridin-4-yl heterocyclyl derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.

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