656239-37-1

Usage

Uses

Used in Organic Synthesis:
N-(tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide serves as a crucial building block in organic synthesis, facilitating the creation of more intricate molecular structures. Its distinct properties allow it to participate in various chemical reactions, making it an indispensable component for synthesizing complex organic compounds.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, N-(tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is utilized for its potential role in drug development. Its unique structure and reactivity contribute to the design and synthesis of new pharmaceutical agents, potentially leading to the discovery of novel therapeutics.
Used in Materials Science:
N-(tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide also finds applications in materials science, where its specific properties can be harnessed to develop new materials with tailored characteristics for various industrial applications.
Used in Chemical Research:
For researchers and scientists in the field of organic chemistry, N-(tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is a valuable tool. Its precise chemical composition and structure provide a foundation for exploring new chemical reactions and transformations, furthering the understanding of organic chemistry and its applications.

Upstream product

• 38041-19-9 4-aminotetrahydropyran 
• 180516-87-4 4-carboxyphenylboronic acid pinacol ester 
• 380499-68-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid chloride 

Downstream Products

• 656257-75-9 2-(6-methylpyridin-2-yl)-1-[2-(4-((tetrahydropyran-4-yl)-aminocarbonyl)phenyl)-pyridin-4-yl]-ethanone 
• 657399-24-1 N-(tetrahydropyran-4-yl)-4-(4-{2-tert-butyl-5-[6-methyl-pyridin-2-yl]-1H-imidazol-4-yl}-pyridin-2-yl)-benzamide 

Relevant academic research and scientific papers

SUBSTITUTED BIPHENYL DERIVATIVE

The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: wherein R1 represents a C6-C10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C1-C6 alkyl)amino group, a di-(C1-C6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C1-C6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R3 represents a C1-C6 alkyl group, and so on; and R4 represents a C1-C6 alkyl group, and so on.

PYRAZOLE INHIBITORS OF THE TRANSFORMING GROWTH FACTOR

The invention relates to novel pyrazole derivatives of formula (I), which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.

PYRIDINYL SUBSTITUTED (1,2,3,)TRIAZOLES AS INHIBITORS OF THE TGF-BETA SIGNALLING PATHWAY

The invention relates to novel triazole derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, m

2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS

This invention relates to novel 2-phenylpyridin-4-yl heterocyclyl derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.