65740-53-6

Upstream product

• 14994-75-3 4-hydroxy-1-phenylquinolin-2(1H)-one 
• 67-66-3 chloroform 
• 59856-29-0 1-Phenyl-3-[1-phenylamino-meth-(Z)-ylidene]-1H-quinoline-2,4-dione 

Downstream Products

• 132279-68-6 3-(4-Methoxy-phenyl)-6-phenyl-6H-pyrano[3,2-c]quinoline-2,5-dione 
• 132279-75-5 N-(2,5-Dioxo-6-phenyl-5,6-dihydro-2H-pyrano[3,2-c]quinolin-3-yl)-acetamide 
• 1190084-78-6 C₂₃H₁₈N₂O₃ 
• 1190084-70-8 4-hydroxy-3-formylidene-2'-nitroanilino-1-phenylquinolin-2-one 
• 1190084-79-7 C₁₉H₁₈N₂O₂ 
• 1190084-69-5 4-hydroxy-3-formylideneanilino-1-phenylquinolin-2-one 
• 105873-04-9 4-hydroxy-3-formylidene-2'-hydroxyoanilino-1-phenylquinolin-2-one 
• 1190084-72-0 C₂₃H₁₈N₂O₂ 
• 148587-01-3 4-Chloro-2-oxo-1-phenyl-1,2-dihydro-quinoline-3-carbaldehyde 
• 59856-42-7 2,5-dioxo-6-phenyl-5,6-dihydro-2H-pyrano[3,2-c]quinoline-3-carboxylic acid ethyl ester 
• 148586-99-6 4-chloro-3-dichloromethyl-1-phenyl-quinolin-2(1H)-one 
• 132279-72-2 2,5-Dioxo-6-phenyl-5,6-dihydro-2H-pyrano[3,2-c]quinoline-3-carboxylic acid phenylamide 
• 132279-65-3 3,6-Diphenyl-6H-pyrano[3,2-c]quinoline-2,5-dione 
• 105873-12-9 C₁₆H₁₂N₂O₃ 

Relevant academic research and scientific papers

Synthesis of 3-amino-4,5-dihydro(5H)4-oxothieno[3,2-c]quinoline-2- carboxylic acids and their alkyl esters

4-Hydroxyquinolin-2(H)ones are converted to 4-chloro-3-cyanoquinolin-2(H) ones and are cyclised with thioglycolic acid and its alkyl esters to furnish the title compounds viz. 3-amino-4,5-dihydro(5H)4-oxothieno[3,2-c]quinoline-2- carboxylic acids and thei

Synthesis of 4-hydroxy-3-formylideneamino-lH/methyl/phenylquinolin-2-ones

An efficient method for the synthesis of 4-hydroxy-3-formylideneamino-l H/methyl/phenylquinolin-2-ones by the condensation of corresponding 4-hydroxy-3-formyl-l///methyl/phenylquinolin-2-one with substituted anilines/aliphatic primary amines is reported. The carboxaldehyde in turn is prepared starting either from substituted anilines or benzoic acid. The structures of compounds are established by the elemental analysis and spectral data.

Alkyl and acyl substituted quinolines

Compounds useful as antiviral agents against DNA-containing viruses, such as herpes group viruses, are disclosed. The compounds are represented by Formula 1.0: STR1 and their pharmaceutically acceptable salts and solvates; wherein: (A) X is selected from

Nucleophilic Chlorination of 3-Formyl-4-hydroxy-quinolin-2(1H)-ones

Chlorination of 1-substituted 3-formyl-4-hydroxy-2-quinolones (1a, b) with phosphorylchloride leads to 4-chloro-3-dichloromethylquinolones (2), which can be hydrolyzed to 4-chloro-3-formylquinolones (4).From the anilinomethylene quinolinediones (3), at lo