657402-34-1Relevant academic research and scientific papers
Tetrazoles: XLVI. 3H-1,3,4-benzo-and pyrido[6,7-b][1,3,4]triazepines from 5-aryltetrazoles. Synthesis and chemical properties
Nikulin,Artamonova,Koldobskii
, p. 1525 - 1529 (2007/10/03)
2,5-Disubstituted 3H-1,3,4-benzotriazepines were synthesized by heating of N-imidoyltetrazoles in toluene at 110°C. Alkylation of these compounds, as well as of 3H-pyrido[6,7-b][1,3,4]triazepines with alkyl halides in THF in the presence of potassium tert-butoxide gave the corresponding 1-alkyl derivatives in good yield and with high regioselectivity.
