657424-10-7Relevant academic research and scientific papers
Synthesis of 3,5-disubstituted 1,2,4-oxadiazoles as peptidomimetic building blocks
Jakopin, ?iga,Ro?kar, Robert,Dolenc, Marija Sollner
, p. 1465 - 1468 (2008/02/02)
Twelve new 1,2,4-oxadiazole based compounds have been synthesized. Their structures contain a protected amine and a carboxyl or an ester group, and thus serve as potential peptidomimetic building blocks. The synthetic route is simple and mild conditions are used so that the chirality of the starting amino acids is retained.
NEW COMPOUNDS
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Page/Page column 57, (2010/11/30)
The present invention relates to new compounds of formula (I), wherein P, Q, X1, X2, X3, X4, R, R1, R2, R3, R4, R5, R6, R7, m, n, o, p and q are defined as in any one of claims 1 to 12, a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.
