657430-21-2Relevant academic research and scientific papers
Benzimidazole- and benzothiazole-quinones: Excellent substrates for NAD(P)H:quinone oxidoreductase 1
Newsome, Jeffery J.,Colucci, Marie A.,Hassani, Mary,Beall, Howard D.,Moody, Christopher J.
, p. 3665 - 3673 (2008/09/21)
A series of benzimidazole- and benzothiazole-quinones has been synthesized. The ability of these heterocyclic quinones to act as substrates for recombinant human NAD(P)H:quinone oxidoreductase (NQO1), a two-electron reductase upregulated in tumour cells,
