65745-70-2

Basic information

• Product Name: 5-methyl-6-nitroquinoline
• Synonyms: 5-methyl-6-nitroquinoline
• CAS NO: 65745-70-2
• Molecular Formula: C10H8N2O2
• Molecular Weight: 188.18272
• Mol File: 65745-70-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-methyl-6-nitroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-6-nitroquinoline(65745-70-2)
• EPA Substance Registry System: 5-methyl-6-nitroquinoline(65745-70-2)

Safety Data

• Hazardous Substances Data: 65745-70-2(Hazardous Substances Data)

Upstream product

• 611-05-2 4-nitro-3-methylaniline 
• 56-81-5 glycerol 
• 51366-39-3 4-acetamido-2-methylnitrobenzene 
• 613-50-3 6-nitroquinoline 
• 693-04-9 butyl magnesium bromide 
• 7664-93-9 sulfuric acid 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 858713-01-6 5-methyl-[6]quinolylamine 

Relevant articles and documents

Selective ortho methylation of nitroheteroaryls by vicarious nucleophilic substitution

(Chemical Equation Presented) An efficient and scalable three-step one-pot approach to 6-methyl-5-nitroisoquinoline (1) from inexpensive 5-nitroisoquinoline, utilizing the vicarious nucleophilic substitution (VNS) as a key step, is described. The optimized reaction conditions can be applied to a limited number of other aromatic and heteroaromatic nitro compounds. Attempts to understand the observed selectivity in the VNS step led to the discovery of two new reaction pathways under VNS conditions, one leading to an isoxazole and the other resulting in the formal cyclopropanation of an aromatic nitro compound.

1-(4-BENZYL-PIPERAZIN-1-YL)-3-PHENYL-PROPENONE DERIVATIVES

A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein the symbols have meaning as defined, which are antagonists of CCR-1 and which find use pharmaceutically for treatment of diseases and conditions in which CCR-1 is i