6578-88-7

Upstream product

• 2002-03-1 2-amino-5-phenyl-1,3,4-thiadiazole 
• 90-02-8 salicylaldehyde 
• 65-85-0 benzoic acid 

Downstream Products

• 72193-01-2 3-(4-chloro-phenoxy)-4-(2-hydroxy-phenyl)-1-(5-phenyl-[1,3,4]thiadiazol-2-yl)-azetidin-2-one 
• 98628-83-2 (C₆H₅C₂N₂SNCHC₆H₄O)2Ni 
• 107548-25-4 UO₂(NO₃)((C₆H₅)C₂N₂S(NCHC₆H₄(OH)))(H₂O)2⁽¹⁺⁾*NO₃^(1-) = [UO₂(NO₃)((C₆H₅)C₂N₂S(NCHC₆H₄(OH)))(H₂O)2][NO₃] 
• 107548-23-2 In(Cl)2((C₆H₅)C₂N₂S(NCHC₆H₄(OH)))(H₂O)2⁽¹⁺⁾*Cl^(1-) = [In(Cl)2((C₆H₅)C₂N₂S(NCHC₆H₄(OH)))(H₂O)2]Cl 
• 98628-82-1 (C₆H₅C₂N₂SNCHC₆H₄O)2Cu 
• 72193-02-3 4-(2-hydroxy-phenyl)-1-(5-phenyl-[1,3,4]thiadiazol-2-yl)-3-p-tolyloxy-azetidin-2-one 

Relevant academic research and scientific papers

Synthesis of 2-N-salicylidene-5-(substituted)-1,3,4-thiadiazole as potential antimicrobial agents

Several new 2,5-disubstituted derivatives of 1,3,4-thiadiazoles containing imine moiety were obtained from cyclization of thiosemicarbazide and corresponding p-substituted carboxylic acid in phosphorus oxychloride then the resulted products were reacted w

Synthesis of Some Azomethine Derivatives of 2-Amino-5-phenyl-1,3,4-thiadiazole

Azomethines derived from 2-amino-5-phenyl-1,3,4-thiadiazole were prepared by fusion of the starling amine with corresponding carhonyl compound. The method ensures yields of target products up to 97%. The composition and structure of the products were conf

Electronic Spectra and Acidity Constants of Hetero-Aromatic Schiff Bases Derived from 2-Amino-5-phenyl-1,3,4-Thiodiazole and Various Aromatic Aldehydes

The different absorption bands observed in the UV and visible electronic spectra of some arylidene 2-amino-1,3,4-thiodiazole are assigned to the possible electronic transitions.This is made in the light of investigating the spectra of the compounds in pur

KINETICS OF ACID-CATALYSED SHIFF BASE FORMATION BETWEEN 2-AMINO-5-PHENYL-1,3,4-THIADIAZOLE AND AROMATIC ALDEHYDES

The kinetics of the acetic acid-catalysed condensation reaction of 2-amino-5-phenyl-1,3,4-thiadiazole (1) with various aromatic aldehydes has been studied in methanol at different temperatures.The reaction was followed kinetically by measuring the absorbance at the maximum absorption wavelength of the Schiff base formed.In the presence of low concentrations of acetic acid, the reaction is kinetically third-order, first-order in each of 1, aldehyde and acetic acid.On the other hand, in the presence of high acetic acid concentrations, (0.15M), the reaction is totally independent of acid concentration.The rate-determining step of the reaction in the presence of acetic acid as catalyst is suggested to be the dehydration of the carbinolamine intermediate 3.The effect of pH of the acid catalyst (i.e. acetic acid and HCl) on the reaction rate is investigated and discussed.The aldehyde structure-reactivity relationship is illustrated.Furthermore, the effect of the nature of the hydroxylic solvent employed as a reaction medium on the rate of the reaction is studied and discussed.

Electronic Spectra and Acidity Constants of Schiff Bases Derived from 2-Amino-5-phenyl-1,3,4-thiadiazole and Various Aromatic Aldehydes

The different absorption bands observed in the UV and visible electronic spectra of some arylidene-2-amino-1,3,4-thiadiazoles in pure and mixed organic solvents of various polarities as well as in buffer solutions have been assigned.The possibility of the