65783-10-0Relevant academic research and scientific papers
Facile synthesis of 2,4-diamino-6-alkyl- or 6-aryl-pyrimidine derivatives
Wang, Xihong,Sathunuru, Ramadas,Melendez, Victor,Kozar, Michael P.,Lin, Ai J.
scheme or table, p. 1056 - 1061 (2010/10/21)
(Chemical Equation Presented) Facile methods were developed to prepare a series of 6-phenyl and 6-alkyl-2,4-diaminopyrimidine derivatives. The pyrimidine ring of the final products was constructed by treatment of a 1,3-dicarbonyl derivative with an amidin
2-Guanidinylimidazolidinedione compounds and methods of making and using thereof
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Page/Page column 7-8; 10; 12-13, (2010/02/12)
Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural formula A or B wherein R1 and R2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R3
Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives
Zhang, Quan,Guan, Jian,Sacci, John,Ager, Arba,Ellis, William,Milhous, Wilbur,Kyle, Dennis,Lin, Ai J.
, p. 6472 - 6481 (2007/10/03)
WR182393, a guanidinoimidazolidinedione derivatives with potent causal prophylactic antimalarial activity by intramuscular injection, was previouly prepared by treatment of chloroproguanil and diethyl oxalate, yielding a mixture of two closely related iso
PYRADAZINE COMPOUNDS AS GSK-3 INHIBITORS
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Page 94-95, (2008/06/13)
The present invention relates generally to inhibitors of the kinases, such as GSK3, and more particularly to fused pyradazine compounds according to formula (I) and methods of their use.
